Michigan-pittsburgh-wyss regenerative medicine resource center: advancing dental, oral, and craniofacial regeneration to clinical trial initiation

Active Cooperative Agreement Awarded Last action

Award ID
U24DE029462
Recipient
Awarding agency
Obligated
$87,594,509

Award facts

Assistance listing
93.121 Oral Diseases and Disorders Research
Completion date 92% complete
Originally
Funding
  • $81,313,433.00 Federal
  • $6,281,076.00 Non-federal
Place of performance
Michigan, USA

Award details come from USAspending.gov.

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment $0 $0
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Amendment -$125,532 $0
Amendment -$125,532 $0
Amendment $6,276,567 $0
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Amendment $6,282,265 $0
Amendment $6,282,265 $0
Amendment $6,282,265 $0
Amendment $6,282,265 $0
Amendment $6,282,265 $0
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Amendment $6,223,509 $0
Amendment $6,223,509 $0
Amendment $0 $0
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Amendment $0 $0
Amendment $6,281,076 $0
Amendment $6,281,076 $6,281,076
Original award $6,314,301 $0
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Subawards

Subrecipient Amount Awarded
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The purpose of this subcontract is for UPitt (Marra) to conduct animal studies (Peripheral nerve in rats) for Amend Surgical. $109,303
President And Fellows Of Harvard College This is an integrated center. The main contribution of Harvard/Wyss will be in the development of manufacturing processes, and fabrication of prototypes. $379,404
Greenmark Biomedical Inc. Dental Caries (tooth decay) is the world’s most prevalent chronic disease affecting about 96% of Americans over their lifetime. In response, GreenMark… -$166,375
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The University of Pittsburgh and the McGowan Institute for Regenerative Medicine provide a structure for cell therapies, pre-clinical large animal models and… $874,552
University Of Pittsburgh - Of The Commonwealth System Of Higher Education -$105,528
Revbio, Inc. The goal of this project is to optimize a synthetic, injectable, cohesive organic-mineral bone graft biomaterial with adhesive properties called Tetranite… $375,777
Greenmark Biomedical Inc. Dental Caries (tooth decay) is the world’s most prevalent chronic disease affecting about 96% of Americans over their lifetime. In response, GreenMark… $326,755
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The University of Pittsburgh and the McGowan Institute for Regenerative Medicine provide a structure for cell therapies, pre-clinical large animal models and… $769,054
President And Fellows Of Harvard College This is an integrated center. The main contribution of Harvard/Wyss will be in the development of manufacturing processes, and fabrication of prototypes. $322,854
Ogb3, Inc. The objective of this work is to develop a new class of immunomodulatory therapies ideal for the treatment of periodontal disease and other oral inflammatory… -$265,016
President And Fellows Of Harvard College Periodontal disease is the leading cause of tooth loss in adults, affecting approximately 50% of the US adult population, with approximately 10% of patients… $67,048
Trustees Of Tufts College This project seeks to develop a hydrogel-based system for endodontic regeneration. $46,787
Amend Surgical, Inc. The goal for the Tissureâ„¢ Project is to conduct robust research and planning, perform extensive prototype testing to refine the specification, conduct… $873,062
Revbio, Inc. The goal of this project is to optimize a synthetic, injectable, cohesive organic-mineral bone graft biomaterial with adhesive properties called Tetranite… $224,294
Amend Surgical, Inc. The goal for the Amend Tissue Tapeâ„¢ Project is to complete the feasibility phase (through design freeze). While validations and regulatory submissions… $1,173,126
Oregon Health & Science University This is a cooperative agreement. NIDCR and the Operating team for the Michigan-Pittsburgh-Wyss Resource Center chose the ITP team from Tufts/Oregon Health and… $1,032,388
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The ultimate goal of this work is to commercialize Vital-Dent, with the initial market indication of vital pulp therapy (VPT) in pulpectomy of irreversible… $899,540
Revbio, Inc. The goal of this project is to optimize a synthetic, injectable, cohesive organic-mineral bone graft biomaterial with adhesive properties called Tetranite… $1,952,734
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The University of Pittsburgh and the McGowan Institute for Regenerative Medicine provide a structure for cell therapies, pre-clinical large animal models and… $5,422,333
President And Fellows Of Harvard College This is an integrated center. The main contribution of Harvard/Wyss will be in the development of manufacturing processes, and fabrication of prototypes. $2,207,509
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Quick answers

Who received award U24DE029462?

U24DE029462 was awarded to Regents Of The University Of Michigan by National Institute of Dental and Craniofacial Research (National Institutes of Health) on May 1, 2020.

How much is award U24DE029462 worth?

$87,594,509 has been obligated on U24DE029462: $81,313,433 in federal funding and $6,281,076 in non-federal funding.

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