Multi-consortia coordinating center (MC2 center) for cancer biology: building interdisciplinary scientific communities, coordinating impactful resource sharing, and advancing cancer research

Active Cooperative Agreement Awarded Last action

Award ID
U24CA274494
Recipient
Awarding agency
Obligated
$25,151,070

Award facts

Assistance listing
93.396 Cancer Biology Research
Completion date 83% complete
Place of performance
Seattle, WA 98121, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Systems biology has been an instrumental approach to overcoming challenges in biomedical research, where solutions arise from interdisciplinary efforts, shared resources (data, tools, models, expertise) and integrative analyses. The NCI division of cancer biology (DCB) has created multiple consortia comprising interdisciplinary communities of scientists who aim to integrate approaches, data, and tools to address important questions in basic and translational cancer research. The multi-consortia coordinating (MC2) center for cancer biology will work across programs to motivate engagement and collaboration, support resource sharing, and disseminate knowledge and resources to the broader scientific community. The MC2 center will operate through three hubs. The collaboration hub will use evidence-based strategies to catalyze interactions and new collaborations. An evaluation framework will be developed with quantitative and qualitative metrics to ensure the center continuously improves its impact. Community engagement activities will include working groups, special interest groups, dream challenges, and ideation jams, all of which will have mechanisms for ensuring inclusion and promoting diversity. To facilitate sharing of resources from DCB programs, the resource coordination hub will ensure all resources are findable, accessible, interoperable and reusable (fair); IT will identify or develop open and fair standards and best practices; provide training on how to implement these standards and practices in the cancer research community; and provide tooling and interfaces to facilitate resource sharing, curation, and deposition in public repositories. Finally, the outreach hub will enhance dissemination of knowledge and resources through training materials to maximize utilization of tools and short courses and workshops that bring concepts and resources from across the DCB programs together, enabling the broader community to experience the power of an integrative interdisciplinary approach to cancer. The cancer complexity knowledge portal will continue to provide open access to all data, tools, and other resources generated through the DCB and MC2, highlighting discoveries and enabling exploration into the many valuable resources generated by DCB programs.

Transactions

Action Obligated Date
Amendment $1,834,442
Amendment -$540
Amendment $188,064
Amendment $188,064
Amendment $175,000
Amendment $175,000
Amendment $175,000
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $1,875,140
Amendment $1,875,140
Amendment $0
Amendment $0
Amendment $0
Amendment $1,793,657
Amendment $1,793,657
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $270,000
Amendment $270,000
Amendment Assuring AI/ML-readiness of digital pathology in diverse existing and emerging multi-omic datasets through quality control workflows $270,000
Amendment Spatial transcriptomics explorer (STE): an open-source resource for visualizing spatial gene expression data $152,500
Amendment $152,500
Amendment $152,500
Amendment Assuring AI/ML-readiness of digital pathology in diverse existing and emerging multi-omic datasets through quality control workflows $152,500
Amendment $1,867,064
Amendment Spatial transcriptomics explorer (STE): an open-source resource for visualizing spatial gene expression data $1,867,064
Amendment $1,867,064
Amendment $1,867,064
Amendment Assuring AI/ML-readiness of digital pathology in diverse existing and emerging multi-omic datasets through quality control workflows $1,867,064
Amendment $1,980,301
Original award $1,980,301
Show all 45

Subawards

Subrecipient Amount Awarded
President And Fellows Of Harvard College The scientific programmer recruited and co-supervised by Instructor Artem Sokolov (Subaward investigator) and Research Associate Clarence Yapp (Co-investigator)… $161,025
Yale Univ The scope of the work for the Yale subcontract with SAGE Bionetworks will include: A. Plan the 2nd Workshop on Physical and Quantitative Methods for Cancer… $80,903
The Regents Of The University Of Colorado Dr. Costello will coordinate with Dr. Banerjee to help organize outreach efforts in collaboration with Sage Bionetworks, including: • Identification of research… $30,537
President And Fellows Of Harvard College The scientific programmer recruited and co-supervised by Instructor Artem Sokolov (Subaward investigator) and Research Associate Clarence Yapp (Co-investigator)… $152,974
Yale Univ The scope of the work for the Yale subcontract with SAGE Bionetworks will include: A. Plan the 2nd Workshop on Physical and Quantitative Methods for Cancer… $74,619
The Regents Of The University Of Colorado Dr. Costello will coordinate with Dr. Banerjee to help organize outreach efforts in collaboration with Sage Bionetworks, including: • Identification of… $29,011
The Leland Stanford Junior University The Stanford and Sage Bionetworks teams will work in partnership to build a pilot version of a web application for exploring spatial transcriptomic data. The… $50,000
Emory University Assuring AI/ML-readiness of digital pathology in diverse existing and emerging multiomic datasets through quality control workflows As Co-I, Dr. Andrew… $125,000
President And Fellows Of Harvard College The scientific programmer recruited and co-supervised by Instructor Artem Sokolov (Subaward investigator) and Research Associate Clarence Yapp (Co-investigator)… $318,830
Yale Univ The scope of the work for the Yale subcontract with SAGE Bionetworks will include: A. Development of training modules and short courses 1) O’Hern and… $165,461
The Regents Of The University Of Colorado University of Colorado Anschutz Medical Campus (Costello lab) Dr. Costello will coordinate with Dr. Bletz to help organize outreach efforts in collaboration… $35,603
University Of Wisconsin System Dr. Rolland will serve as a co-Investigator for the MC2 Coordinating Center. She will co-lead the Collaboration Hub with Kaitlyn Flynn of Sage Bionetworks.… $92,700
Show all 12

Quick answers

Who received award U24CA274494?

U24CA274494 was awarded to Sage Bionetworks by National Cancer Institute (National Institutes of Health) on September 14, 2022.

How much is award U24CA274494 worth?

$25,151,070 has been obligated on U24CA274494.

On GovTribe

See this award's full record

  • Every transaction and subaward
  • The recipient's other awards and teaming partners
  • Similar grant awards
  • Ask GovTribe AI about this award
Try for free Login