Sustaining the integrative imaging informatics for cancer research (I3CR) center

Active Cooperative Agreement Awarded Last action

Award ID
U24CA258483
Recipient
Awarding agency
Obligated
$12,052,822

Award facts

Assistance listing
93.394 Cancer Detection and Diagnosis Research
Completion date 93% complete
Originally
Funding
  • $10,458,602.00 Federal
  • $1,594,220.00 Non-federal
Place of performance
St. Louis, MO 63110, USA

Award details come from USAspending.gov.

Description

Abstract
Artificial intelligence (AI) and other computationally intensive methods have the potential to revolutionize cancer imaging research and patient care. The broad adoption of these technologies depends on the availability development of imaging informatics tools to assist users in managing massive data sets, generating well-curated annotations, and accessing scalable computing resources. The integrative imaging informatics for cancer research (I3CR) center has played a lead role in implementing cancer imaging informatics technology, with a focus on expanding the widely used open source xnat informatics platform to better support computational workflows in cancer imaging. I3CR has also developed knowledge management tools to better track data processing and analysis, including tools for orchestrating and tracking container-based computing pipelines. As result of this work, xnat has emerged as the most widely used imaging informatics platform in cancer research. IT is deployed in over 200 organizations across academia and industry and has been adopted across a wide range of research contexts, including preclinical imaging, multi-site clinical trials, and clinical translation. As the I3CR informatics platform has matured and been widely adopted, the center is now evolving to the next phase of development to more broadly sustain the platform. In the work proposed here, we will sustain the I3CR's ongoing engineering initiatives and expand its outreach efforts. The center's sustainment activities will build on and extend the I3CR platform's expansive set of data and knowledge management capabilities, with a focus on addressing key emergent needs within our user base. In aim 1, we will continue to develop the xnat-based data management platform, including adding standards-based clinical interfaces, developing a cohort discovery service with natural language processing support, implementing a task automation service, and extending its container-based computing service to support high performance computing and cloud computing environments. In aim 2, we will implement a suite of integrations with complementary image analysis and data sharing platforms, including the cancer image archive and the NCI imaging data commons. In aim 3, we will expand the I3CR's outreach initiatives to ensure broad and effective adoption of the I3CR informatics platforms. The center's training program will utilize the xnat academy education platform to host a series of online training programs directed at specific audiences including developers, data scientists, integrators, and system administrators. A suite of supporting cloud services will be implemented assist the community in adopting and developing on the I3CR platform.

Transactions

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Subawards

Subrecipient Amount Awarded
The Univeristy Of Texas M.d. Anderson Cancer Center COPE OF WORK – Subrecipient: The University of Texas MD Anderson Cancer Center – Caroline Chung Project: Sustaining the Integrative Imaging Informatics for… $51,621
The Univeristy Of Texas M.d. Anderson Cancer Center SCOPE OF WORK – The University of Texas MD Anderson Cancer Center SPECIFIC AIMS The parent grant, Sustaining the Integrative Imaging Informatics for… $0
Institute Of Cancer Research: Royal Cancer Hospital (The) Statement of work and deliverables Dr Doran has a longstanding history of collaboration with the XNAT team, is a regular participant on the XNAT Discussion… $0
The Univeristy Of Texas M.d. Anderson Cancer Center SCOPE OF WORK – The University of Texas MD Anderson Cancer Center SPECIFIC AIMS The parent grant, Sustaining the Integrative Imaging Informatics for… $40,517
The Univeristy Of Texas M.d. Anderson Cancer Center SCOPE OF WORK – The University of Texas MD Anderson Cancer Center SPECIFIC AIMS The parent grant, Sustaining the Integrative Imaging Informatics for… $39,481
Institute Of Cancer Research: Royal Cancer Hospital (The) Statement of work and deliverables Dr Doran has a longstanding history of collaboration with the XNAT team, is a regular participant on the XNAT Discussion… $125,628

Quick answers

Who received award U24CA258483?

U24CA258483 was awarded to The Washington University by National Cancer Institute (National Institutes of Health) on April 6, 2021.

How much is award U24CA258483 worth?

$12,052,822 has been obligated on U24CA258483: $10,458,602 in federal funding and $1,594,220 in non-federal funding.

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