Overture: a multi-scale data platform for cancer genomics research

Active Cooperative Agreement Awarded Last action

Award ID
U24CA253529
Recipient
Awarding agency
Obligated
$5,809,159

Award facts

Assistance listing
93.396 Cancer Biology Research
Completion date 86% complete
Originally
Funding
  • $5,274,535.00 Federal
  • $534,624.00 Non-federal
Place of performance
2323 Riverside Dr., Ottawa, ON K1H 1A1, Canada

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Overture is a collection of modular, open-source software components designed to make the management of big-data genomic projects both easy and more cost effective. The overture system promotes fair data sharing of cancer genomic datasets by overcoming the major obstacles in storing, managing, exploring, and distributing massive genome-scale datasets. In this proposed project, we will implement a turnkey overture data management system (DMS) to provide a complete solution to manage cancer genomic data throughout the data life cycle, and to continue lowering the technical barriers faced by researchers in the cancer informatics community. To extend the capabilities and potential of the overture DMS, we will establish a new software framework for integration with third-party visualization applications, and for data exchange with analysis platforms. This framework will empower the community to continue developing extremely valuable visualization applications for specific research interests and datatypes, and to contribute them as "apps" to be integrated with the overture DMS. Over the next five years, we will: (1) combine the core set of overture components into a scalable DMS installation bundle to promote both local and cloud deployment for a range of small to consortia-scale datasets; (2) extend the DMS with third-party visualization and analysis tools through a novel software data integration framework; (3) enhance data access controls by implementing global alliance for genomics and health (GA4GH) passport and data use ontology standards; (3) enable federated searching within cancer datasets across different overture platforms; and (4) improve outreach and community resources to meet the needs of bioinformaticians, data producers and managers, data scientists, and clinical researchers. The overture DMS will be a valuable resource for removing complications of large-scale data management from researchers, allowing the advancement of scientific research by increasing data sharing and discovery.

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment $537,348 $0
Amendment $0 $0
Amendment $0 $0
Amendment $510,481 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $526,064 $0
Amendment $526,064 $0
Amendment $526,064 $0
Amendment $526,064 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $526,601 $0
Amendment $526,601 $0
Amendment $534,624 $0
Original award $534,624 $534,624
Show all 33

Quick answers

Who received award U24CA253529?

U24CA253529 was awarded to Ontario Institute For Cancer Research Institut Ontarien De Recherche SUR LE Cancer by National Cancer Institute (National Institutes of Health) on September 9, 2021.

How much is award U24CA253529 worth?

$5,809,159 has been obligated on U24CA253529: $5,274,535 in federal funding and $534,624 in non-federal funding.

On GovTribe

See this award's full record

  • Every transaction and subaward
  • The recipient's other awards and teaming partners
  • Similar grant awards
  • Ask GovTribe AI about this award
Try for free Login