Cooperative Agreement U24AI189369
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $452,475 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Colorado State University (CSU) to study adaptive immune responses in bats. The project aims to determine the effector functions of helper and cytotoxic T cells in response to bat influenza A and coronavirus infections, and evaluate the impacts of vaccination and T cell depletion on infection control. CSU will use a captive...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $455,692 Project Grant to the University of California, Berkeley to conduct research on the mechanisms that underpin bat virus virulence. The goal is to experimentally test predictions from the research team's theoretical model by carrying out experimental evolution of Vesicular Stomatitis Virus (VSV) in bat cell cultures that...
- This $451,836 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research grant program (CFDA 93.855), to The Washington University in Missouri. The purpose of the grant is to conduct a structural and mechanistic study of the bat NLRP6 inflammasome and its role in detecting RNA viruses, such as Ebola, Nipah, Hendra, and SARS-CoV, which bats can host without developing significant disease symptoms. The research...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $150,452 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Oklahoma. The grant will support a project titled "Molecular Testing of Predicted Bat Hosts for Zoonotic Hemoplasmas" from September 2025 to August 2027. The project aims to use machine learning models to prioritize bat species for molecular testing to identify potential zoonotic reservoirs of...
- This federal Project Grant award of $464,296 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research on the impact of bat hibernation on metabolism and immunity to infection. The award recipient, the University of Wisconsin System, will conduct studies to understand how temperature changes during hibernation affect the metabolic functions and immune responses of bat keratinocytes and...
- This Project Grant award of $376,932 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), will support research on the relationship between stress, migration, and viral shedding in Mexican free-tailed bats (Tadarida brasiliensis). The key objectives are to characterize coronavirus (CoV) diversity and infection status in bat populations, quantify stress physiology, and develop new cell lines...
- The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, awarded a $805,375 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai. The grant, awarded on November 20, 2024, supports a 5-year research project to elucidate the cellular tropism, receptor usage, and pathogenesis mechanisms of emerging bat-derived pararubulaviruses, which pose a potential global health...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $146,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Ghana to assess mechanisms for the persistence of RNA viruses in bat populations. The 5-year project, running from September 2025 to August 2030, aims to study virus prevalence, shedding, and spillover risk in captive and wild colonies of the straw-colored fruit bat (Eidolon helvum) in Ghana. The...
- This Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $425,612 to conduct in-depth biophysical and functional analyses of three antibody lineages (CM10, CM11, and CM12) that target the GP2 wing region of the Marburg virus glycoprotein. The research aims to determine the structural basis for antibody recognition and protective function of this region,...
- The University of Texas Southwestern Medical Center (UT Southwestern) received a $454,726 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The purpose of this 5-year award, with a start date of July 9, 2025 and a completion date of June 30, 2030, is to investigate cell-intrinsic antiviral mechanisms in bats, focusing on interferon-stimulated genes (ISGs) and their evolutionary...
This Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to develop pan-reactive monoclonal antibodies (mAbs) and cytokine reagents for immunologic analysis of bats. The $495,061 award to Integral Molecular Inc. will fund research to generate mAbs and cytokine reagents that can be used across most or all bat species, addressing a scarcity of immunologic research tools for the bat research community. The project, which has a final completion date of June 30, 2030, seeks to provide a comprehensive set of mAbs and cytokine reagents to support various research applications and enable a better understanding of the immune response in bats, which can aid in the response to viral outbreaks and other diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $495.1k | 8/19/25 |