Consortium for immunotherapeutics against emerging viral threats

Ended Cooperative Agreement Awarded Last action

Award ID
U19AI142790
Recipient
Awarding agency
Obligated
$78,802,914

Award facts

Assistance listing
93.855 Allergy and Infectious Diseases Research
Completion date
Originally
Funding
  • $69,833,931.17 Federal
  • $8,968,983.00 Non-federal
Place of performance
La Jolla, CA 92037, USA

Award details come from USAspending.gov.

Transactions

Action Federal Non-federal Date
Amendment -$179,678 $0
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Amendment $1,903,653 $0
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Amendment $7,065,330 $0
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Amendment $2,688,763 $0
Amendment $7,143,424 $0
Original award $7,168,390 $0
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Subawards

Subrecipient Amount Awarded
Public Health Agency Of Canada In general, PHAC will be responsible for performing efficacy testing of selected VIC antibodies or antibody cocktails against filoviruses in the ferret or… $84,560
Vanderbilt University Medical Center Crowe Project 2 Objective- To conduct antibody discovery campaigns for new human monoclonal antibodies to filoviruses and generate and characterize panels of… $616,909
The Washington University In Aim 1, the Diamond lab will characterization the cell binding and neutralizing activity of human pan-alphavirus mAbs. In addition, we will assess mAb binding… $562,552
The General Hospital Corporation Boris Juelg, MD, PhD, will advise on the transition of agents developed by the consortium from preclinical into early phase clinical studies and will… $7,050
The Washington University For Core 1, Dr. Fremont will develop mAbs that have Fv domains that are engineered to have enhanced binding characteristics and developability. To develop these… $108,864
University Of Texas Medical Branch At Galveston Zalgen Labs is developing broadly neutralizing human monoclonal antibodies (mAbs) that afford protection among all four lineages of Lassa virus (LASV). No FDA… $544,716
Purdue University The former Rossman lab (now overseen by Richard Kuhn) and the Kuhn lab will participate in Project 3 Development of therapeutic pan-Alphavirus human… $138,125
University Of Wisconsin System Dr. Yoshihiro Kawaoka - University of Wisconsin-Madison Dr. Kawaoka’s group will generate and characterize escape mutant viruses using chimeric… $77,311
Emory University At Emory University we will be performing additional antibody discovery using the samples taken from the four Ebola patients treated at Emory University… $143,316
Oregon Health & Science University ALPHAVIRUSES are members of the Togaviridae family and include a number of emerging arthropod-borne viruses that cause severe and often life-threatening disease… $520,364
Friedrich-Alexander-Universitat Erlangen-Nurnberg The main task of Dr. Falk Nimmerjahn is to provide functional assays to delineate if the virus specific IgG antibodies isolated by the consortium partners may… $100,870
University Of Pittsburgh - Of The Commonwealth System Of Higher Education The work to be conducted in this subcontract involves treatment of Rhesus macaques with an anti-VEEV antibody cocktail or control antibody cocktail either 24… $311,950
Zalgen Labs LLC Zalgenâ€TMs main responsibilities in Project 1 will be to produce recombinant human antibodies at 100 mg to multi-gram scale to support in vivo studies… $989,912
The Administrators Of Tulane Educational Fund Objectives, tasks and deliverables to be performed by the subrecipient. Specific Aim 1. Complete pre-clinical evaluation of arevirum-3. Completion of chemistry,… $307,507
Massachusetts Institute Of Technology Douglas Lauffenburger will serve as an Investigator on this project, supervising certain aspects of computational analysis contributions to the overall study.… $134,100
The General Hospital Corporation The Alter lab will generate and validate the constructs necessary to produce functionally enhanced monoclonal antibodies in vivo. The will also test the… $232,203
University Of Texas Medical Branch At Galveston The following work will be performed by DR. Burkeyev , his staff and the support of personnel of the UTMB and Galveston National Library: Analysis of… $415,645
Purdue University The former Rossman lab (now overseen by Richard Kuhn) and the Kuhn lab will participate in Project 3 Development of therapeutic pan-Alphavirus human… $202,814
University Of California, LOS Angeles As part of a collaboration with the La Jolla Institute for Allergy and Immunology's application for the Consortium for Advanced Development of Antiviral… $145,075
Public Health Agency Of Canada In general, PHAC will be responsible for performing efficacy testing of selected VIC antibodies or antibody cocktails against filoviruses in the ferret or… $528,793
University Of Texas Medical Branch At Galveston Zalgen Labs is developing broadly neutralizing human monoclonal antibodies (mAbs) that afford protection among all four lineages of Lassa virus (LASV). No FDA… $420,195
Zalgen Labs LLC Zalgenâ€TMs main responsibilities in Project 1 will be to produce recombinant human antibodies at 100 mg to multi-gram scale to support in vivo studies… $919,549
The General Hospital Corporation The Alter lab will generate and validate the constructs necessary to produce functionally enhanced monoclonal antibodies in vivo. The will also test the… $235,053
The Washington University For Core 1, Dr. Fremont will develop mAbs that have Fv domains that are engineered to have enhanced binding characteristics and developability. To develop these… $105,578
Friedrich-Alexander-Universitat Erlangen-Nurnberg The main task of Dr. Falk Nimmerjahn is to provide functional assays to delineate if the virus specific IgG antibodies isolated by the consortium partners may… $102,108
Oregon Health & Science University ALPHAVIRUSES are members of the Togaviridae family and include a number of emerging arthropod-borne viruses that cause severe and often life-threatening disease… $608,979
Massachusetts Institute Of Technology Douglas Lauffenburger will serve as an Investigator on this project, supervising certain aspects of computational analysis contributions to the overall study.… $135,746
Emory University At Emory University we will be performing additional antibody discovery using the samples taken from the four Ebola patients treated at Emory University… $145,075
Vanderbilt University Medical Center Crowe Project 2 Objective- To conduct antibody discovery campaigns for new human monoclonal antibodies to filoviruses and generate and characterize panels of… $734,685
The Washington University In Aim 1, the Diamond lab will characterization the cell binding and neutralizing activity of human pan-alphavirus mAbs. In addition, we will assess mAb binding… $602,831
The Administrators Of Tulane Educational Fund Objectives, tasks and deliverables to be performed by the subrecipient. Specific Aim 1. Complete pre-clinical evaluation of arevirum-3. Completion of chemistry,… $305,807
University Of Texas Medical Branch At Galveston The following work will be performed by DR. Burkeyev , his staff and the support of personnel of the UTMB and Galveston National Library: Analysis of… $469,279
The General Hospital Corporation Boris Juelg, MD, PhD, will advise on the transition of agents developed by the consortium from preclinical into early phase clinical studies and will… $7,136
Show all 33

Quick answers

Who received award U19AI142790?

U19AI142790 was awarded to La Jolla Institute For Immunology by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on July 27, 2020.

How much is award U19AI142790 worth?

$78,802,914 has been obligated on U19AI142790: $69,833,931 in federal funding and $8,968,983 in non-federal funding.

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