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Cooperative Agreement U19AI109761
Award Date
3/7/14
Completion Date
2/29/20
Dollars Obligated
$31M
Overview
Activity
Transactions
6
Subawards
22
Federal Agency
National Institute of Allergy and Infectious Diseases
Awardee
The Trustees Of Columbia University In The City Of New York (QHF5ZZ114M72)
Federal Grant Program
93.855
Assistance Type
Cooperative Agreement
Place of Performance
New York, NY 10032, USA
Description
Update #1
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
Posted 2/28/14, 12:00 AM
Mod #
Description
Reason For Modification
Federal Obligation
(Click to sort descending)
Date
(Click to sort ascending)
Not listed
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
($1m)
9/22/20
Not listed
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
$6.2m
2/23/18
Not listed
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
$6.6m
2/24/17
Not listed
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
$212.6k
8/19/16
Not listed
CENTER FOR RESEARCH IN DIAGNOSTICS AND DISCOVERY
$385.7k
6/30/16
Grant Number
Description
Subgrantee
Prime Award
Dollars Obligated
(Click to sort descending)
Updated At
(Click to sort ascending)
2GG008377S
Early diagnosis of systemic infection in humans and prediction of clinical outcome both remain elusive, despite the critical need for both. The two basic approaches for diagnosis and prognosis, direct identification of the infectious agent and measurement of host response features, have been limited by reliance on cultivation, pre-test assumptions about specific agents, limited breadth of coverage and an insufficient signal-to-noise ratio. The goals of this project are to characterize microbial and viral genomic sequences in the peripheral blood of healthy subjects as well as subjects with fever (and in some cases, know causative infectious agents) at the time of clinical presentation, to characterize human genome-wide RNS patters in peripheral blood, and then to integrate these complementary forms of data so as to derive putative diagnostic and prognostic signatures for systemic infection.
The Leland Stanford Junior University
Cooperative Agreement U19AI109761
$0
4/15/15
7GG00837712S
This project is divided into two parts, both of which investigate novel approaches to defining host signatures associated with and/or predictive of severe dengue disease or conversely, protection against sever disease. The primary purpose of part 1 is to establish a proof-of-concept for an immunocompetent murine model of DENV-induced vascular leak and to define the gene expression profile of severe dengue disease in wild-type mice.
The Regents Of The University Of California
Cooperative Agreement U19AI109761
$167.8k
7/23/15
2GG00837719S
Early diagnosis of systemic infection in humans and prediction of clinical outcome both remain elusive, despite the critical need for both. The two basic approaches for diagnosis and prognosis, direct identification of the infectious agent and measurement of host response features, have been limited by reliance on cultivation, pre-test assumptions about specific agents, limited breadth of coverage and an insufficient signal-to-noise ratio. The goals of this project are to characterize microbial and viral genomic sequences in the peripheral blood of healthy subjects as well as subjects with fever (and in some cases, know causative infectious agents) at the time of clinical presentation, to characterize human genome-wide RNS patters in peripheral blood, and then to integrate these complementary forms of data so as to derive putative diagnostic and prognostic signatures for systemic infection.
The Leland Stanford Junior University
Cooperative Agreement U19AI109761
$689.2k
5/24/16
5GG008377S
Theoverall goal of this program is to develop new platform technologies to rapidly recover and characterize new and emerging viruses in vitro and in vivo. Secondary objectives are to use functional genomics as diagnostic and prognostic indicators of virulence and disease severity following virus infection of the lung
University Of North Carolina At Chapel Hill
Cooperative Agreement U19AI109761
$0
6/11/15
6GG008337706S
The translation core is designed to support CRDD projects by collecting and supplying well characterized specimens from humans, domestic animals and wildlife with infectious diseases and providing access to CLIA laboratories at the New York State Department of Health Wadsworth Center and NYC Department of Health and Mental Hygiene that are staffed with public health personnel who have specific expertise in optimizing and validating diagnostic assays for clinical use.
Ecohealth Alliance Inc.
Cooperative Agreement U19AI109761
$0
5/8/15