Cooperative Agreement U10CA063848

Federal Cooperative Agreement Award Summary The University of Michigan's Regents, through its Office of Research and Sponsored Projects, received a $210,600 Cooperative Agreement from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) effective September 1, 2025, through August 31, 2027. This award supports the analytical and clinical validation of an H3K27M circulating tumor DNA (ctDNA) assay for diffuse midline glioma (DMG) surveillance. The...

Federal Cooperative Agreement Summary The National Cancer Institute (NCI) awarded a Cooperative Agreement totaling $323,226 to the Regents of the University of Michigan, effective August 1, 2025, through July 31, 2028, under the Cancer Cause and Prevention Research program (CFDA 93.393). This award supports research focused on developing natural products to target Interleukin-8 (IL-8) signaling pathways with the objective of intercepting the progression of Barrett's esophagus to esophageal...

Federal Project Grant Award Summary The University of Michigan's Regents received a $646,920 Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395), effective March 11, 2026 through February 28, 2031. This award supports research into novel multi-targeted therapeutic strategies for T-cell lymphomas (TCL) that are chemotherapy-resistant and refractory to existing targeted agents. The research addresses the multifactorial mechanisms...

Federal Cooperative Agreement Summary The Michigan Department of Health and Human Services (MDHHS) received a Cooperative Agreement award of $813,280 from the Centers for Disease Control and Prevention (CDC) National Center for Chronic Disease Prevention and Health Promotion under the Organized Approaches to Increase Colorectal Cancer Screening program (CFDA 93.800), effective August 30, 2025, through August 29, 2030. This five-year award funds the Michigan Colorectal Cancer Control Program...

Federal Project Grant Award Summary The University of Michigan's Regents, through its Office of Research and Sponsored Projects Division, received a $165,080 Project Grant award from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) for the project "Receipt of Guideline Concordant Surveillance in Young Colorectal Cancer Patients." The award was obligated on February 4, 2026, with a completion date of August 31, 2027. This project delivers...

Federal Grant Award Summary The University of Michigan's Regents, through its Office of Research and Sponsored Projects, received a $319,505 Project Grant from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) effective August 1, 2025, through July 31, 2030. This award funds the development and delivery of comprehensive training in methodologies for adapting and personalizing cancer control interventions across the continuum of care—including cancer risk...

Federal Grant Award Summary The University of Michigan received a $2.82 million Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), awarded August 6, 2025, with a completion date of July 31, 2029. The project focuses on developing new methodologies to measure and interrupt metabolic fluxes in glioblastomas (GBMs), highly aggressive brain cancers that currently lack effective treatment strategies despite standard resection, radiation, and...

Federal Project Grant Award Summary The National Cancer Institute awarded the Regents of the University of Michigan a Project Grant totaling $2,864,671 on September 10, 2025, under the Cancer Treatment Research program (CFDA 93.395) to develop and evaluate a novel microbial-based therapeutic strategy targeting colibactin, a carcinogenic metabolite produced by enteric bacteria associated with colorectal cancer (CRC). The research centers on two primary deliverables: (1) engineering...

Federal Cooperative Agreement Summary The National Cancer Institute (NCI) awarded the University of Wisconsin–Madison a $2.49M Cooperative Agreement under the Cancer Control program (CFDA 93.399) beginning August 5, 2025, and extending through July 31, 2031. This award establishes the CP-CTNET (Cancer Prevention Clinical Trials Network) Coordinating Center, which serves as the administrative and operational hub for early-phase clinical trials designed to assess the safety, tolerability, and...

Federal Project Grant Award Summary The National Cancer Institute (NCI), under the Cancer Research Manpower program (CFDA 93.398), awarded a Project Grant of $162,305 to the Regents of the University of Michigan, with an award date of August 1, 2025 and completion date of July 31, 2030. This award supports a mentored research training project led by Dr. Peggy Hsu, MD, PhD, a physician-scientist developing expertise in early detection and characterization of anaplastic lymphoma kinase...