Washington university school of medicine undiagnosed diseases network clinical site
Active Cooperative Agreement Awarded Last action
- Award ID
- U01NS134354
- Recipient
-
The Washington University UEI L6NFUM28LQM5
- Awarding agency
-
National Institute of Neurological Disorders and Stroke
National Institutes of Health, Department of Health and Human Services
- Obligated
- $8,880,577
Award facts
- Assistance listing
- 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders
- Completion date 82% complete
- Originally
- Place of performance
- St. Louis, MO 63110, USA
Award details come from USAspending.gov.
Description
- Abstract
- The scientific premise of this application is that the individualized translational research process of the undiagnosed diseases network (UDN) is sustainable and that its impact on patients, families, and disease discovery can be further extended by increasing its accessibility to a broader participant population. This application would support the washington university in ST. Louis (wustl) UDN clinical site. Wustl school of medicine and BJC healthcare together represent a large academic medical center, hospital, and outpatient clinical system that is fully integrated with world-renowned basic science capabilities and demonstrated expertise in finding diagnoses for patients with undiagnosed diseases. The highly collaborative clinical and biomedical research culture at wustl school of medicine promotes interactions within and across departments, with institutional genomic, clinical, computational, and model system experts, and with colleagues regionally, nationally, and internationally. These interactions support recruitment, selection, evaluation, diagnosis discovery, and follow up of pediatric and adult patients with undiagnosed diseases through both established networks and individual referrals. Building on this infrastructure, we propose to continue to advance the success of the UDN in diagnosing and managing disease in undiagnosed patients by creating a new system for clinical and genomic review of applications and participant cases, with expanded clinical expertise to solve cases that are not suspected to have genetic underpinnings. Second, we aim to improve equity and access to the UDN for participants from underserved populations. In particular, we will focus our outreach program for underrepresented minority populations and populations with lower socioeconomic status. Third, we will develop and implement a sustainability plan that will shift the cost burden from research support where possible, while maintaining access for participants who are uninsured, under- insured, or otherwise unable to pay. We will work closely with the UDN network and coordinating center to study the barriers to achieving these goals and propose strategies to solve them.
Transactions
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| Amendment | $311,000 | |
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Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| The ST. Louis Integrated Health Network | $87,193 | |
| The ST. Louis Integrated Health Network | $90,603 |
Quick answers
Who received award U01NS134354?
U01NS134354 was awarded to The Washington University by National Institute of Neurological Disorders and Stroke (National Institutes of Health) on September 21, 2018.
How much is award U01NS134354 worth?
$8,880,577 has been obligated on U01NS134354.
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