Sickle hemoglobinopathy research in zimbabwe (shaz)

Active Cooperative Agreement Awarded Last action

Award ID
U01HL156943
Recipient
Awarding agency
Obligated
$1,789,226

Award facts

Assistance listing
93.837 Cardiovascular Diseases Research
Completion date 92% complete
Originally
Funding
  • $1,681,226.00 Federal
  • $108,000.00 Non-federal
Place of performance
Zimbabwe

Award details come from USAspending.gov.

Description

Abstract
/summary the goal of the sickle hemoglobinopathy research in zimbabwe (shaz) application is to establish a sustainable infrastructure and operation aimed at addressing the limited data and gaps in sickle cell disease (SCD) management that currently exists in zimbabwe and zambia by contributing to the SCD in sub-saharan africa (SSA) network consortium registry and biorepository. Shaz aims to create accomplished SCD clinicians and research personnel who will focus on introduction and implementation of the SCD in SSA network registry efforts, enrolling at least 4,000 individuals with SCD from zambia and zimbabwe over a five-year period. The shaz team will aim to integrate regional SCD evidence-based management guidelines and will develop three cohort studies to generate more evidence on heritability of clinical phenotype of SCD, describing the natural history and clinical correlates of adverse outcomes in SCD patients specifically the association between abnormal cerebral blood flow and foetal hemoglobin level as a risk factor for stroke. Furthermore, implementation science research will be utilized as a tool to promote uptake of the evidence-based practices that improve outcomes in SCD patients namely: newborn screening, improved nutrition and hydroxyurea use in the two countries.

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment $9,925 $0
Amendment $9,925 $0
Amendment $230,605 $0
Amendment $230,605 $0
Amendment $235,696 $0
Amendment $159,911 $0
Amendment $159,911 $0
Amendment $160,324 $0
Amendment $160,324 $0
Amendment $108,000 $0
Amendment $108,000 $0
Original award $108,000 $108,000
Show all 13

Quick answers

Who received award U01HL156943?

U01HL156943 was awarded to Faculty Of Medicine And Health Sciences University Of Zimbabwe by National Heart Lung and Blood Institute (National Institutes of Health) on May 20, 2021.

How much is award U01HL156943 worth?

$1,789,226 has been obligated on U01HL156943: $1,681,226 in federal funding and $108,000 in non-federal funding.

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