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All Federal Grant Awards
Cooperative Agreement U01HL138647
Award Date
9/1/17
Completion Date
5/31/23
Dollars Obligated
$2.5M
Overview
Activity
12
Transactions
12
Subawards
Similar Awards
Federal Agency
National Heart Lung and Blood Institute
Awardee
Instituto De Nutricion De Centro America Y Panama (H9ESWURV7N66)
Federal Grant Program
93.837
Assistance Type
Cooperative Agreement
Place of Performance
45-54, A Aguilar Batres Sur, Cdad. de Guatemala, Guatemala
Update #1
Update #2
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA
Posted 9/1/17
5
1
2
3
Mod #
Description
ReasonForModification
Federal Obligation
Date
Not listed
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA - PROJECT SUMMARY DESPITE ADVANCES IN HYPERTENSION PREVENTION AND TREATMENT RESEARCH, ITS PREVALENCE IS HIGH AND INCREASING, WHILE THE PROPORTIONS OF HYPERTENSIVE PATIENTS WHO ARE AWARE, TREATED, AND CONTROLLED ARE LOW, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES (LMIC). WE PROPOSE TO: ASSESS THE NEEDS, BARRIERS, AND KNOWLEDGE GAPS OF HYPERTENSION CONTROL PROGRAMS IN THE NATIONAL HEALTH CARE SYSTEMS OF THE CENTRAL AMERICA 4 REGION LMIC (CA- 4: GUATEMALA, HONDURAS, EL SALVADOR, AND NICARAGUA); CONDUCT A CLUSTER RANDOMIZED TRIAL TO TEST THE EFFECT OF A MULTILEVEL AND MULTICOMPONENT INTERVENTION PROGRAM ON BLOOD PRESSURE (BP) CONTROL AMONG GUATEMALAN HYPERTENSIVE PATIENTS; AND EVALUATE THE ADAPTABILITY, FEASIBILITY, FIDELITY, AND SUSTAINABILITY OF IMPLEMENTING THE PROGRAM IN THE PRIMARY HEALTH CARE SYSTEMS OF THE CA-4 REGION. WE WILL CONDUCT FORMATIVE RESEARCH TO ASSESS THE NEEDS OF SYSTEM-WIDE INTERVENTION PROGRAMS, BARRIERS AND FACILITATORS OF BP CONTROL STRATEGIES, AND KNOWLEDGE GAPS ABOUT IMPLEMENTATION FOR IMPROVING HYPERTENSION CONTROL IN THE CA-4 HEALTH CARE SYSTEMS. THE PROPOSED TRIAL WILL RECRUIT 1,770 STUDY PARTICIPANTS FROM 32 PRIMARY CARE DISTRICTS (55 PATIENTS AGED 22 YEARS WITH UNCONTROLLED HYPERTENSION/DISTRICT) WITHIN A SUBNATIONAL PRIMARY CARE NETWORK MANAGED BY THE GUATEMALAN MINISTRY OF HEALTH. SIXTEEN HEALTH DISTRICTS WILL BE ASSIGNED TO AN 18-MONTH MULTICOMPONENT INTERVENTION, WHICH INCLUDES PROTOCOL-BASED TREATMENT USING: A STANDARD BLOOD PRESSURE (BP) MANAGEMENT ALGORITHM, TEAM-BASED COLLABORATIVE CARE, BP AUDIT AND FEEDBACK, HOME BP MONITORING, AND HEALTH COACHING ON ANTIHYPERTENSIVE MEDICATION ADHERENCE AND LIFESTYLE MODIFICATION, AND 16 TO USUAL CARE. THE STUDY WILL USE AN EFFECTIVENESS-IMPLEMENTATION HYBRID TYPE 2 DESIGN TO TEST EFFECTIVENESS OF THE MULTICOMPONENT INTERVENTION PROGRAM. BP AND OTHER INDICATORS WILL BE MEASURED AT BASELINE AND AT MONTHS 6, 12, AND 18. THE PRIMARY CLINICAL OUTCOME IS THE DIFFERENCE IN THE PROPORTION OF PATIENTS WITH CONTROLLED BP (
$0
5/14/24
Not listed
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA - PROJECT SUMMARY DESPITE ADVANCES IN HYPERTENSION PREVENTION AND TREATMENT RESEARCH, ITS PREVALENCE IS HIGH AND INCREASING, WHILE THE PROPORTIONS OF HYPERTENSIVE PATIENTS WHO ARE AWARE, TREATED, AND CONTROLLED ARE LOW, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES (LMIC). WE PROPOSE TO: ASSESS THE NEEDS, BARRIERS, AND KNOWLEDGE GAPS OF HYPERTENSION CONTROL PROGRAMS IN THE NATIONAL HEALTH CARE SYSTEMS OF THE CENTRAL AMERICA 4 REGION LMIC (CA- 4: GUATEMALA, HONDURAS, EL SALVADOR, AND NICARAGUA); CONDUCT A CLUSTER RANDOMIZED TRIAL TO TEST THE EFFECT OF A MULTILEVEL AND MULTICOMPONENT INTERVENTION PROGRAM ON BLOOD PRESSURE (BP) CONTROL AMONG GUATEMALAN HYPERTENSIVE PATIENTS; AND EVALUATE THE ADAPTABILITY, FEASIBILITY, FIDELITY, AND SUSTAINABILITY OF IMPLEMENTING THE PROGRAM IN THE PRIMARY HEALTH CARE SYSTEMS OF THE CA-4 REGION. WE WILL CONDUCT FORMATIVE RESEARCH TO ASSESS THE NEEDS OF SYSTEM-WIDE INTERVENTION PROGRAMS, BARRIERS AND FACILITATORS OF BP CONTROL STRATEGIES, AND KNOWLEDGE GAPS ABOUT IMPLEMENTATION FOR IMPROVING HYPERTENSION CONTROL IN THE CA-4 HEALTH CARE SYSTEMS. THE PROPOSED TRIAL WILL RECRUIT 1,770 STUDY PARTICIPANTS FROM 32 PRIMARY CARE DISTRICTS (55 PATIENTS AGED 22 YEARS WITH UNCONTROLLED HYPERTENSION/DISTRICT) WITHIN A SUBNATIONAL PRIMARY CARE NETWORK MANAGED BY THE GUATEMALAN MINISTRY OF HEALTH. SIXTEEN HEALTH DISTRICTS WILL BE ASSIGNED TO AN 18-MONTH MULTICOMPONENT INTERVENTION, WHICH INCLUDES PROTOCOL-BASED TREATMENT USING: A STANDARD BLOOD PRESSURE (BP) MANAGEMENT ALGORITHM, TEAM-BASED COLLABORATIVE CARE, BP AUDIT AND FEEDBACK, HOME BP MONITORING, AND HEALTH COACHING ON ANTIHYPERTENSIVE MEDICATION ADHERENCE AND LIFESTYLE MODIFICATION, AND 16 TO USUAL CARE. THE STUDY WILL USE AN EFFECTIVENESS-IMPLEMENTATION HYBRID TYPE 2 DESIGN TO TEST EFFECTIVENESS OF THE MULTICOMPONENT INTERVENTION PROGRAM. BP AND OTHER INDICATORS WILL BE MEASURED AT BASELINE AND AT MONTHS 6, 12, AND 18. THE PRIMARY CLINICAL OUTCOME IS THE DIFFERENCE IN THE PROPORTION OF PATIENTS WITH CONTROLLED BP (
$0
3/5/24
Not listed
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA - PROJECT SUMMARY DESPITE ADVANCES IN HYPERTENSION PREVENTION AND TREATMENT RESEARCH, ITS PREVALENCE IS HIGH AND INCREASING, WHILE THE PROPORTIONS OF HYPERTENSIVE PATIENTS WHO ARE AWARE, TREATED, AND CONTROLLED ARE LOW, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES (LMIC). WE PROPOSE TO: ASSESS THE NEEDS, BARRIERS, AND KNOWLEDGE GAPS OF HYPERTENSION CONTROL PROGRAMS IN THE NATIONAL HEALTH CARE SYSTEMS OF THE CENTRAL AMERICA 4 REGION LMIC (CA- 4: GUATEMALA, HONDURAS, EL SALVADOR, AND NICARAGUA); CONDUCT A CLUSTER RANDOMIZED TRIAL TO TEST THE EFFECT OF A MULTILEVEL AND MULTICOMPONENT INTERVENTION PROGRAM ON BLOOD PRESSURE (BP) CONTROL AMONG GUATEMALAN HYPERTENSIVE PATIENTS; AND EVALUATE THE ADAPTABILITY, FEASIBILITY, FIDELITY, AND SUSTAINABILITY OF IMPLEMENTING THE PROGRAM IN THE PRIMARY HEALTH CARE SYSTEMS OF THE CA-4 REGION. WE WILL CONDUCT FORMATIVE RESEARCH TO ASSESS THE NEEDS OF SYSTEM-WIDE INTERVENTION PROGRAMS, BARRIERS AND FACILITATORS OF BP CONTROL STRATEGIES, AND KNOWLEDGE GAPS ABOUT IMPLEMENTATION FOR IMPROVING HYPERTENSION CONTROL IN THE CA-4 HEALTH CARE SYSTEMS. THE PROPOSED TRIAL WILL RECRUIT 1,770 STUDY PARTICIPANTS FROM 32 PRIMARY CARE DISTRICTS (55 PATIENTS AGED =22 YEARS WITH UNCONTROLLED HYPERTENSION/DISTRICT) WITHIN A SUBNATIONAL PRIMARY CARE NETWORK MANAGED BY THE GUATEMALAN MINISTRY OF HEALTH. SIXTEEN HEALTH DISTRICTS WILL BE ASSIGNED TO AN 18-MONTH MULTICOMPONENT INTERVENTION, WHICH INCLUDES PROTOCOL-BASED TREATMENT USING: A STANDARD BLOOD PRESSURE (BP) MANAGEMENT ALGORITHM, TEAM-BASED COLLABORATIVE CARE, BP AUDIT AND FEEDBACK, HOME BP MONITORING, AND HEALTH COACHING ON ANTIHYPERTENSIVE MEDICATION ADHERENCE AND LIFESTYLE MODIFICATION, AND 16 TO USUAL CARE. THE STUDY WILL USE AN EFFECTIVENESS-IMPLEMENTATION HYBRID TYPE 2 DESIGN TO TEST EFFECTIVENESS OF THE MULTICOMPONENT INTERVENTION PROGRAM. BP AND OTHER INDICATORS WILL BE MEASURED AT BASELINE AND AT MONTHS 6, 12, AND 18. THE PRIMARY CLINICAL OUTCOME IS THE DIFFERENCE IN THE PROPORTION OF PATIENTS WITH CONTROLLED BP (
$0
3/5/24
Not listed
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA - PROJECT SUMMARY DESPITE ADVANCES IN HYPERTENSION PREVENTION AND TREATMENT RESEARCH, ITS PREVALENCE IS HIGH AND INCREASING, WHILE THE PROPORTIONS OF HYPERTENSIVE PATIENTS WHO ARE AWARE, TREATED, AND CONTROLLED ARE LOW, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES (LMIC). WE PROPOSE TO: ASSESS THE NEEDS, BARRIERS, AND KNOWLEDGE GAPS OF HYPERTENSION CONTROL PROGRAMS IN THE NATIONAL HEALTH CARE SYSTEMS OF THE CENTRAL AMERICA 4 REGION LMIC (CA- 4: GUATEMALA, HONDURAS, EL SALVADOR, AND NICARAGUA); CONDUCT A CLUSTER RANDOMIZED TRIAL TO TEST THE EFFECT OF A MULTILEVEL AND MULTICOMPONENT INTERVENTION PROGRAM ON BLOOD PRESSURE (BP) CONTROL AMONG GUATEMALAN HYPERTENSIVE PATIENTS; AND EVALUATE THE ADAPTABILITY, FEASIBILITY, FIDELITY, AND SUSTAINABILITY OF IMPLEMENTING THE PROGRAM IN THE PRIMARY HEALTH CARE SYSTEMS OF THE CA-4 REGION. WE WILL CONDUCT FORMATIVE RESEARCH TO ASSESS THE NEEDS OF SYSTEM-WIDE INTERVENTION PROGRAMS, BARRIERS AND FACILITATORS OF BP CONTROL STRATEGIES, AND KNOWLEDGE GAPS ABOUT IMPLEMENTATION FOR IMPROVING HYPERTENSION CONTROL IN THE CA-4 HEALTH CARE SYSTEMS. THE PROPOSED TRIAL WILL RECRUIT 1,770 STUDY PARTICIPANTS FROM 32 PRIMARY CARE DISTRICTS (55 PATIENTS AGED =22 YEARS WITH UNCONTROLLED HYPERTENSION/DISTRICT) WITHIN A SUBNATIONAL PRIMARY CARE NETWORK MANAGED BY THE GUATEMALAN MINISTRY OF HEALTH. SIXTEEN HEALTH DISTRICTS WILL BE ASSIGNED TO AN 18-MONTH MULTICOMPONENT INTERVENTION, WHICH INCLUDES PROTOCOL-BASED TREATMENT USING: A STANDARD BLOOD PRESSURE (BP) MANAGEMENT ALGORITHM, TEAM-BASED COLLABORATIVE CARE, BP AUDIT AND FEEDBACK, HOME BP MONITORING, AND HEALTH COACHING ON ANTIHYPERTENSIVE MEDICATION ADHERENCE AND LIFESTYLE MODIFICATION, AND 16 TO USUAL CARE. THE STUDY WILL USE AN EFFECTIVENESS-IMPLEMENTATION HYBRID TYPE 2 DESIGN TO TEST EFFECTIVENESS OF THE MULTICOMPONENT INTERVENTION PROGRAM. BP AND OTHER INDICATORS WILL BE MEASURED AT BASELINE AND AT MONTHS 6, 12, AND 18. THE PRIMARY CLINICAL OUTCOME IS THE DIFFERENCE IN THE PROPORTION OF PATIENTS WITH CONTROLLED BP (
$325.2k
7/28/21
Not listed
IMPLEMENTING A MULTICOMPONENT INTERVENTION TO IMPROVE HYPERTENSION CONTROL IN CENTRAL AMERICA - PROJECT SUMMARY DESPITE ADVANCES IN HYPERTENSION PREVENTION AND TREATMENT RESEARCH, ITS PREVALENCE IS HIGH AND INCREASING, WHILE THE PROPORTIONS OF HYPERTENSIVE PATIENTS WHO ARE AWARE, TREATED, AND CONTROLLED ARE LOW, ESPECIALLY IN LOW- AND MIDDLE-INCOME COUNTRIES (LMIC). WE PROPOSE TO: ASSESS THE NEEDS, BARRIERS, AND KNOWLEDGE GAPS OF HYPERTENSION CONTROL PROGRAMS IN THE NATIONAL HEALTH CARE SYSTEMS OF THE CENTRAL AMERICA 4 REGION LMIC (CA- 4: GUATEMALA, HONDURAS, EL SALVADOR, AND NICARAGUA); CONDUCT A CLUSTER RANDOMIZED TRIAL TO TEST THE EFFECT OF A MULTILEVEL AND MULTICOMPONENT INTERVENTION PROGRAM ON BLOOD PRESSURE (BP) CONTROL AMONG GUATEMALAN HYPERTENSIVE PATIENTS; AND EVALUATE THE ADAPTABILITY, FEASIBILITY, FIDELITY, AND SUSTAINABILITY OF IMPLEMENTING THE PROGRAM IN THE PRIMARY HEALTH CARE SYSTEMS OF THE CA-4 REGION. WE WILL CONDUCT FORMATIVE RESEARCH TO ASSESS THE NEEDS OF SYSTEM-WIDE INTERVENTION PROGRAMS, BARRIERS AND FACILITATORS OF BP CONTROL STRATEGIES, AND KNOWLEDGE GAPS ABOUT IMPLEMENTATION FOR IMPROVING HYPERTENSION CONTROL IN THE CA-4 HEALTH CARE SYSTEMS. THE PROPOSED TRIAL WILL RECRUIT 1,770 STUDY PARTICIPANTS FROM 32 PRIMARY CARE DISTRICTS (55 PATIENTS AGED =22 YEARS WITH UNCONTROLLED HYPERTENSION/DISTRICT) WITHIN A SUBNATIONAL PRIMARY CARE NETWORK MANAGED BY THE GUATEMALAN MINISTRY OF HEALTH. SIXTEEN HEALTH DISTRICTS WILL BE ASSIGNED TO AN 18-MONTH MULTICOMPONENT INTERVENTION, WHICH INCLUDES PROTOCOL-BASED TREATMENT USING: A STANDARD BLOOD PRESSURE (BP) MANAGEMENT ALGORITHM, TEAM-BASED COLLABORATIVE CARE, BP AUDIT AND FEEDBACK, HOME BP MONITORING, AND HEALTH COACHING ON ANTIHYPERTENSIVE MEDICATION ADHERENCE AND LIFESTYLE MODIFICATION, AND 16 TO USUAL CARE. THE STUDY WILL USE AN EFFECTIVENESS-IMPLEMENTATION HYBRID TYPE 2 DESIGN TO TEST EFFECTIVENESS OF THE MULTICOMPONENT INTERVENTION PROGRAM. BP AND OTHER INDICATORS WILL BE MEASURED AT BASELINE AND AT MONTHS 6, 12, AND 18. THE PRIMARY CLINICAL OUTCOME IS THE DIFFERENCE IN THE PROPORTION OF PATIENTS WITH CONTROLLED BP (
$325.2k
7/28/21