Cooperative Agreement U01DK143330
- This federal Cooperative Agreement award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to evaluate the use of continuous ketone monitors to enable safe use of SGLT inhibitor medications in patients with type 1 diabetes. The $2,257,919 award to the University of California, San Diego (UC San Diego) will support a two-arm, cross-over clinical trial...
- This $194,654 federal Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) is for a 2-part outpatient study to assess the use of continuous ketone monitoring (CKM) to reduce ketosis and diabetic ketoacidosis (DKA) in individuals with type 1 diabetes using sodium-glucose-linked cotransporter 2 (SGLT2) inhibitor medications. The study, led by principal investigator Ahmad...
- This Cooperative Agreement award of $2,367,892 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund research to develop and evaluate a novel approach to mitigate the risk of diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) and chronic kidney disease (CKD) who are taking sodium-glucose cotransporter (SGLT) inhibitor medications. The project aims...
- This Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to develop and test a risk mitigation strategy using continuous ketone monitoring (CKM) to enable safer use of SGLT2 inhibitors in patients with Type 1 Diabetes (T1D). The $2,477,577 award to Adventist Health System/Sunbelt Inc. (doing business as AdventHealth Orlando) will fund a...
- This $380,466 Cooperative Agreement, awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a study titled "CARDIOVASCULAR AND RENAL PROTECTION WITH SGLT2 INHIBITION IN KIDNEY TRANSPLANT RECIPIENTS (RENAISSANCE)". The project aims to examine the potential benefits and risks of using sodium-glucose cotransporter-2 (SGLT2) inhibitor drugs in kidney...
- This $166,953 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant was awarded to the Regents of the University of Minnesota, Office of Sponsored Projects Administration, to conduct a pilot, pragmatic, cluster-randomized clinical trial to evaluate the feasibility of an intervention to increase the use of SGLT2 inhibitor medications after...
- This Cooperative Agreement award, in the amount of $816,325.00, was granted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award will support a collaborative research project to optimize and evaluate novel small molecule "PAIR" inhibitors that target the unfolded protein response (UPR) pathway in pancreatic beta cells, with the goal of preventing and...
- The federal Project Grant award, "GLUCOSE PATTERNS AND CLINICAL OUTCOMES IN THE DALLAS HEART STUDY: A PATHWAY TO PRECISION DIABETES - CONTINUOUS GLUCOSE MONITORING (CGM) SYSTEMS", is provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $819,091 award to The Johns Hopkins University will fund research to use CGM and machine learning methods to identify...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $235,403 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Johns Hopkins University. The funding will support the development of a membrane-reconstituted ZNT8 biosensor to detect cell-surface ZNT8 autoantibodies in the peripheral blood of patients with type-1 diabetes. This novel bioanalytical tool aims to enable the early detection of islet...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $762,556 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Aurora Health Care, Inc. The award supports the development of a novel, semi-automated self-monitoring feedback system for health promotion in community settings. The project aims to optimize the efficacy of feedback messages related to dietary intake, physical activity, and weight...
This Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide $987,196 to the University of Melbourne in Australia to conduct a randomized-controlled study on the use of continuous glucose and ketone monitoring to minimize diabetic ketoacidosis in individuals with type 1 diabetes treated with the SGLT inhibitor sotagliflozin. The study aims to evaluate the appropriate ketone thresholds for initiating a response to preempt the development of diabetic ketoacidosis, a serious complication associated with the use of SGLT inhibitors in this patient population. The project will run from September 2025 through August 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $987.2k | 9/11/25 |