Communityrx ? Chronic kidney disease (CRX-CKD)? An EMR-integrated community resources referral intervention to address structural racism and kidney health disparities in rural north carolina

Active Cooperative Agreement Awarded Last action

Award ID
U01DK137262
Recipient
Awarding agency
Obligated
$6,619,246

Award facts

Completion date 65% complete
Place of performance
Chapel Hill, NC 27599, USA

Award details come from USAspending.gov.

Description

Abstract
Mitigating progressive chronic kidney disease (CKD) to avoid kidney failure is well known -- management of CKD and its multimorbidity (hypertension, diabetes, obesity, and cardiovascular disease). Yet unequal access to and utilization of quality medical and social resources present a significant and under-addressed barrier to optimal management, especially in rural settings. As advocated by the national academies, we propose to address the endemic effects of structural racism and systemic drivers of health by using an intervention that integrates medical with social care for african americans adults in rural eastern north carolina. The intervention, communityrx (CRX), systematically matches people to nearby community resources using evidence-based algorithms at the point of care with a health care provider. CRX utilizes a three- pronged approach to address integrated care among patients and caregivers: (a) comprehensive, ongoing assessment of community resources (eligibility, capacity, quality) using feet-on-the street (see meaningful active productive science in service to communities (mapscorps) below) and phone survey methods; (b) integration of a simple automatic resource referral process into routine, electronic health record (EHR)-based clinical workflows; and (c) availability of a community resource navigator. CRX for CKD (CRX-CKD) is an application of this infrastructural approach to address CKD multimorbidity. Our community-engaged and multidisciplinary health equity research team will leverage our infrastructural intervention and implementation science expertise to test the effects of CRX-CKD through three related aims. Aim 1 will contextualize implementation and effectiveness of a rural infrastructural integrated care intervention by (a) building an inclusive model with system science to describe how structural racism affects CKD progress on and its mitigation through integrated care; and (b) conducting a network analysis to evaluate structures of clinic-community connectivity. Aim 2 will optimize CRX-CKD implementation through the consolidated framework of implementation research to ensure organizational readiness, fidelity, and acceptability. With aim 3, we will test the effectiveness of the CRX-CKD intervention with a pragmatic cluster randomized controlled trial at the clinic level. Three hundred seventy-five african american individuals with CKD multimorbidity at the intervention clinics will be compared to 375 individuals at usual care clinics for the primary outcome of reduction of the glomerular filtration slope decline and reduction of albuminuria; other, secondary outcomes include control of blood pressure, control of blood sugar, weight reduction, and blood lipid management.

Transactions

Action Obligated Date
Amendment $699,044
Amendment Communityrx-chronic kidney disease (CRX-CKD) in rural north carolina - approximately one in seven adults in the united states lives with chronic kidney… $787,537
Amendment $0
Amendment Communityrx-chronic kidney disease (CRX-CKD) in rural north carolina - approximately one in seven adults in the united states lives with chronic kidney… $0
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Amendment Communityrx-chronic kidney disease (CRX-CKD) in rural north carolina - approximately one in seven adults in the united states lives with chronic kidney… $0
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Amendment $694,999
Amendment $694,999
Amendment $694,999
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Amendment $761,917
Amendment $761,917
Amendment $761,917
Original award $761,917
Show all 19

Subawards

Subrecipient Amount Awarded
The University Of Chicago The University of Chicago will contribute expertise on all aspects of the implementation of the CRx-CKD intervention, including workflow design and… $497,563
Goshen Medical Center, Inc. Goshen Medical Center will partner across all aims of the CRx-CKD study and serve as the intervention site for pragmatic trial to test the CRx-CKD community… $322,426
Project Momentum, Inc. Project Momentum will facilitate engagement, recruitment, and data collection under Aim 1 (Social Networking Analysis and Group Model Building; be the main… $94,157

Quick answers

Who received award U01DK137262?

U01DK137262 was awarded to University Of North Carolina At Chapel Hill by National Institute of Diabetes and Digestive and Kidney Diseases (National Institutes of Health) on September 1, 2023.

How much is award U01DK137262 worth?

$6,619,246 has been obligated on U01DK137262.

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