Cooperative Agreement U01CE003495

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $903,697 to the University of Nebraska at Omaha to conduct research aimed at understanding the neurophysiological mechanisms underlying chronic ankle instability. The objective is to determine functional and neurophysiological differences between subgroups of chronic ankle instability in order to develop more effective, evidence-based rehabilitation approaches. The research involves...

This federal Project Grant award of $632,382 from the National Institute on Aging (CFDA 93.866 Aging Research program) supports a 5-year randomized controlled trial to examine the effects of a 6-month Tai Chi intervention on chronic pain, cognition, cognitive-motor function, fear of falling, and rate of falls in 266 older adults with multisite pain and fall risk. The trial will measure pain severity, pain interference, fear of falling, pain-related biomarkers, cognition, gait function,...

This Project Grant award of $673,012 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research to understand the neuromechanical bases for the increased energy cost of walking in aging. The University of Massachusetts is the primary awardee, with the goal of determining how age-related changes in gait strategy combine with muscle weaknesses to increase the energy cost of walking in older adults. The research will address key knowledge gaps regarding relative...

The National Institute on Aging (NIA) awarded a $613,823 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The purpose of this 5-year grant, beginning September 1, 2025, is to assess the effectiveness of the SENSE4SAFETY technology-supported intervention in reducing fall risk for community-dwelling older adults with mild cognitive impairment. The...

This Project Grant award from the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE, CFDA 47.070) program aims to develop and evaluate a new auto-calibrated insole system, along with explainable artificial intelligence (XAI) models, to enable accurate, tailored, and reliable fall risk assessment for adults aged 65 and older during their normal daily routines. The $441,032 award to the University of New Hampshire will advance technologies that...

The University of Kansas Medical Center Research Institute, Inc. (KUMCRI) received a $435,582 Project Grant award from the National Institute on Aging (NIA) under the Aging Research grant program (CFDA 93.866) to study the mechanisms of head and neck control during falls in balance-impaired older adults. The project aims to determine how vestibular function and neck muscle mechanics contribute to head control during laboratory-induced falls and head perturbations. The research team, which...

This Project Grant award of $224,580.00, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) federal grant program, supports research to investigate the role of muscle spindles in the control of balance and movement. The research, conducted by Emory University, aims to combine computational modeling of muscle spindle dynamics with direct recordings of muscle spindle activity and fascicle...

This $1,610,219 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846), will fund a 5-year longitudinal study examining the relationship between muscle quantity, quality, function, and biomarkers with changes in bone density, microarchitecture, and strength in older adults. The University of Pittsburgh will conduct this research, which aims to...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports the development of an ultrasound-coupled electrical impedance tomography (US-EIT) device for assessing sarcopenia, a condition involving loss of skeletal muscle mass and function. The $275,762 award to Rytek Medical Inc. will be used to design a sonolucent electrode array and housing that integrates with a standard ultrasound probe, enabling quantitative evaluation of muscle health through...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $3,126,515 to Trustees of Indiana University in Indianapolis, IN to conduct research aimed at understanding how the L-BAIBA/FGF23 axis, an interaction between muscle and bone, can be targeted to enhance musculoskeletal health and resilience in aging populations. The research seeks to elucidate the mechanisms by which this muscle-bone signaling pathway becomes dysregulated with age, leading to...