Project Grant R44MH124334

BETTERBOT: Accessible Mental Health Support for Individuals with Traumatic Brain Injury Docbotic Inc. received a $499,887 Project Grant from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), effective September 1, 2025 through August 31, 2026. The award funds the development and evaluation of BETTERBOT, an Short Message Service (SMS) chatbot application that leverages artificial intelligence and large language models to deliver...

The National Institute of Mental Health (NIMH) awarded a $156,500 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Emory University to identify patients with true treatment failure for major depressive disorder (MDD) who may benefit from earlier referral to alternative treatments like transcranial magnetic stimulation, ketamine, and vagus nerve stimulation. The project aims to use trajectory classification methods to empirically separate partial response from true...

Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Texas Health Science Center at Houston a $1.34 million Project Grant under the Mental Health Research Grants program (CFDA 93.242) on June 4, 2025, to conduct a randomized controlled trial testing the effectiveness of telehealth-delivered behavioral activation (Tele-BA-S) for preventing post-stroke depression in low-income older stroke survivors. The research initiative, titled "Behavioral...

Federal Cooperative Agreement Summary Brigham & Women's Hospital Inc. received a $3.376 million Cooperative Agreement from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), effective September 1, 2025, through August 31, 2027. The award funds the development of dynamic decision support tools for precision treatment-resistant depression (TRD) care. The primary deliverable is a clinical decision support system (CDSS) that employs dynamic...

The National Institutes of Health National Center for Complementary and Integrative Health awarded New York University $785,637 under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) from June 2021 through May 2025. This Cooperative Agreement will support the development and pilot testing of telephone-delivered and video-based Mindfulness-Based Cognitive Therapy (MBCT) protocols for patients with migraine headaches and depressive symptoms. Specifically, the...

Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded McLean Hospital a $777,016 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective July 1, 2025, through April 30, 2030. This research project investigates the synaptic mechanisms of continuous theta burst stimulation (cTBS), an FDA-cleared repetitive transcranial magnetic stimulation (rTMS) protocol used to treat treatment-resistant depression. The primary deliverables include...

This federal Project Grant award, titled "MAINTENANCE RTMS FOR DEPRESSION (MAITR-DE)", is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The $968,769 award will support a multi-site study to investigate the efficacy of maintenance repetitive transcranial magnetic stimulation (rTMS) in sustaining treatment response for individuals with treatment-resistant depression. The study will be conducted by the University of...

Federal Project Grant Award Summary The University of Wisconsin-Madison received a $1.56 million Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to conduct a four-year research study (August 1, 2025 – July 31, 2029) optimizing the integration of human and digital support components within the Healthy Minds Program (HMP), a widely-used meditation application for treating depression and anxiety. The research...

This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $178,319 to the University of California, San Diego (UC San Diego) for the development and testing of a novel personalized suicide prevention intervention called PRECISE. The award supports refinement of the PRECISE intervention using a user-centered design approach in Aim 1, followed by a randomized controlled trial in Aim 2 to compare two...

The National Science Foundation (NSF) Directorate for Engineering awarded the University of Pittsburgh a 3-year, $350,000 Project Grant to develop an innovative closed-loop brain-computer interface (BCI) system for use in exposure therapy for socially fearful teenagers with depression and anxiety. The proposed technology synchronizes electroencephalogram (EEG) monitoring with augmented reality (AR) simulations of social fear scenarios, enabling real-time detection of fearful responses and...