Project Grant R44DE027903

This $294,632 federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) aims to develop an intraoral camera system that can detect and monitor early-stage dental caries (tooth decay) using targeted fluorescent nanoparticle technology. The awarded project, led by Greenmark Biomedical Inc., will prepare a minimally viable product (MVP) of the intraoral camera system and conduct...

This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, provides $309,428 to support the development of a novel optical pH (OPH) device for early-stage detection and monitoring of dental caries. The awardee, Veravanti Inc., aims to create a medical imaging product that combines high-resolution color imaging with precise pH mapping capabilities, enabling dentists to rapidly...

The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $619,347 Project Grant under the Oral Diseases and Disorders Research Program (CFDA 93.121) to Light Research Inc., a small business based in Tucson, Arizona. The grant funds the development and optimization of a compact multimodal intraoral camera that integrates polarized white light imaging, autofluorescence imaging, optical coherence tomography, and near-infrared transillumination imaging modalities. This advanced...

The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $295,689 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to Callentis Consulting Group LLC, a woman-owned small business. This 1-year grant supports the development of high-performance, bisphenol A (BPA)-free dental restoration composites with remineralization capabilities. The project aims to develop novel urethane-based composite resins that exhibit superior mechanical properties,...

The University of Kansas Center for Research Inc. was awarded a $467,008 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), to develop a novel non-invasive treatment for dental caries in children and patients with special needs. The project aims to create a biomimetic peptide-polymer interface that works synergistically with silver diamine fluoride (SDF) to arrest caries progression and...

This federal Project Grant award, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop near-infrared chemiluminescent and fluorescent chitosan-based nanoparticles (CNPs) to improve detection of micrometastatic cancer and guide image-guided surgery. With a total funding amount of $466,500.00 over a 3-year period from September 2024 to September 2027, the research will explore the use of...

This Project Grant award, valued at $164,255.00 and provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop innovative dental materials capable of inhibiting microbial biofilm formation while preserving commensal oral bacteria. The key objectives are to: 1) synthesize a 2-aminoimidazole derivative (H10) and create a new methacrylate-based antimicrobial agent containing covalently...

This Project Grant from the National Science Foundation supports the development of superparamagnetic, antimicrobial nanocomposites and a magnetic toothbrush for synergistic dental care. Awarded $276,000 on June 1, 2022 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the funding will support MNT Smartsolutions LLC through May 31, 2023. The company will develop a biofunctionalized magnetic nanoparticle ferropaste that can efficiently remove oral bacterial biofilms...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) Project Grant award of $275,000 aims to validate a novel device and approach for enhancing the delivery of pharmaceuticals and cosmetics into human teeth. The key products and services to be delivered under this award include: Validating the use of electrical voltage, current, application time, pressure, and conductive additives to improve the permeability and depth of delivery for topical...

This federal Project Grant award of $310,000 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a novel primer for the reversible bonding and debonding of high-strength dental ceramics. The University of Mississippi Medical Center (UMMC) is the primary awardee. The key objectives are to: 1) Characterize the bonding and debonding capabilities of lithium disilicate and partially stabilized...