Project Grant R43CA250885

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is providing $1,337,953.41 to the University of Arizona to develop and disseminate an advanced 2-photon Bessel beam light sheet (2PBLS) microscopy instrument for high-speed, sub-micron resolution volumetric imaging in deep tissue. The proposed instrument will enable faster...

This Project Grant award, totaling $623,622, was provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The goal is to develop a novel Probe-based Light Sheet Microscopy (PLSM) device and evaluate its clinical utility for in vivo imaging to aid anal cancer screening. The project, which runs from January 2025 to December 2028, involves a...

This federal Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $942,983 to acquire a Bruker Luxendo TruLive3D light-sheet microscope system. The award, effective September 1, 2024 through August 31, 2025, will enable rapid 3D volumetric imaging of live specimens such as mouse, fly, and zebrafish embryos with high resolution and minimal phototoxicity. This advanced microscope system will benefit a user group of...

The National Science Foundation awarded $256,000 to Optave Diagnostics LLC through the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a prototype endoscopic probe for molecular imaging and diagnosis of cancerous prostate pathologies. The 12-month project grant will support the creation of a medical device using photoacoustic imaging and acoustic lens technology to aid in the detection and diagnosis of prostate cancer. The proposed endoscopic probe offers an alternative...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Lightfinder Inc. aims to develop a silicon photonic optical coherence tomography (OCT) imager for pathology diagnostics. The primary objective is to create a high-performance, portable, and cost-effective imaging solution by integrating all optical components onto a single silicon chip. The research will address key technical challenges such as achieving high...

The University of Maryland, Baltimore was awarded a $1,799,728.98 Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director to purchase a state-of-the-art light sheet fluorescence microscope. The microscope will be situated in the university's established Confocal Core Facility, which will oversee use, training, and service of the instrument for nine NIH-funded research teams. Light sheet fluorescence microscopy is well-suited for...

This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP, CFDA 93.351) will provide $1,386,474 to Baylor College of Medicine to acquire a Femtonics ATLAS microscope system. The ATLAS microscope combines two-photon excitation with acousto-optical deflector scanning, enabling rapid, high-resolution 3D imaging of neuronal activity using fluorescent reporters. This state-of-the-art imaging system will support a diverse portfolio of...

This Project Grant award of $400,000 from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to develop a new high-speed 3D dynamic contrast microscopic optical coherence tomography (3D DYC-μOCT) imaging system. The goal is to enable label-free, 3D visualization of ciliary beating dynamics in human airway organoids, which is essential for studying lung diseases and developing improved treatments. The key objectives are to: (1) engineer a broadband, high-coherence...

This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $590,000 to the University of Miami to acquire a Leica Stellaris 5 upright confocal microscope. The new microscope will replace an obsolete, end-of-life confocal system and continue to provide high-resolution intravital imaging capabilities to support the NIH-funded research of 9 major user groups across 5 departments at the university. The advanced Stellaris...