Project Grant R43CA239930

This Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $554,188 to The Trustees of the University of Pennsylvania to develop novel silver telluride nanoparticle contrast agents for use in dual-energy mammography breast cancer screening. The goal is to create an improved contrast agent that addresses limitations of current iodine-based agents, providing stronger contrast, a longer imaging window, and better...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $616,033 to the University of California, Davis to develop and validate a PET-enabled dual-energy CT (DECT) imaging method. The goal is to create a technique that can derive a high-energy gamma-ray CT (GCT) image from standard PET/CT emission data, and combine it with...

This Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $666,670 to The Trustees of the University of Pennsylvania to develop innovative scan protocols that combine long axial field-of-view PET and spectral CT imaging for improved quantification in oncology. The goal is to create methods and protocols to obtain high-quality dynamic information from both PET and CT modalities, and to use dynamic spectral CT for PET...

This $536,954 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) will fund research and development of a novel ultra-high-spatial resolution computed tomography (UHR-CT) system using photon-counting detectors and multiple x-ray focal spots. The research aims to overcome limitations of current high-resolution CT systems by developing...

The National Cancer Institute (NCI) awarded a $2,007,264 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to Voximetry Inc. in Madison, WI. The grant, titled "TORCH RECON: AN INNOVATIVE RECONSTRUCTION SOFTWARE FOR INCREASED THROUGHPUT AND IMPROVED LOW-COUNT QUANTITATIVE SPECT IMAGING", will fund the development of advanced SPECT imaging reconstruction software. The software aims to address limitations of traditional SPECT reconstruction methods by...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $2,090,971 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Massachusetts General Hospital (MGH) on August 8, 2024. The DEEPTOBIDX project aims to develop and validate a two-pronged approach to enhance diffusion optical tomography (DOT) for improved breast cancer diagnosis. Key objectives include: 1) Integrating high-density DOT...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...

The National Science Foundation awarded Malcova Inc. $1,000,000 under the Technology, Innovation, and Partnerships federal grant program (CFDA 47.084) to develop a novel non-planar spectral breast computed tomography device. Malcova will use the one-year project grant term from May 1, 2023 to April 30, 2024 to further the device's design, build a working prototype, and conduct validation testing using anthropomorphic phantoms. The non-invasive breast CT device employs a new scanning method and...

This Project Grant award of $305,000.00 from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of an innovative breast cancer screening technology by Bired Imaging Inc. The project aims to create an efficient thermal-spatial point-cloud extraction and rapid assessment of physics-based AI algorithm from infrared images to improve early detection of breast cancer, especially in women with dense breast tissue....

The National Cancer Institute (NCI) awarded a $400,000 Project Grant under CFDA 93.394 (Cancer Detection and Diagnosis Research) to O2M Technologies LLC to develop a Multifunctional Imager (MFI) that can simultaneously acquire tissue oxygen pressure (pO2) and pH maps using electron paramagnetic resonance imaging (EPRI) techniques. The 12-month project aims to create a 25 MT Halbach-type permanent magnet, new multi-modal transmit-receive electronics, and the integrated MFI instrument. This...