Cooperative Agreement R43CA193134

The University of Michigan was awarded a $1.8 million project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program to purchase a Leica SP8 confocal microscope. The microscope will support over 30 investigators at the University engaged in diabetes, vision, and retinal research by replacing two aging microscopes in the university's shared imaging facility. The new microscope will provide high-speed resonant scanning...

This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $740,044 to The Johns Hopkins University to acquire an Olympus FV4000 confocal microscope. This advanced microscope system will address key limitations in current confocal microscopy technology, enabling enhanced multiplexing, spatial resolution, imaging speed, and automated stability for time-lapse imaging of complex biological systems. The new...

The National Institutes of Health (NIH) awarded a $749,854 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Albany Medical College to acquire an Olympus FVMPE-RS multiphoton microscope for intravital microscopy research. This specialized microscope will enable NIH-supported investigators at Albany Medical College and other nearby research institutions to conduct detailed mechanistic studies using mouse models of disease, covering a range of research areas including...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Lightfinder Inc. aims to develop a silicon photonic optical coherence tomography (OCT) imager for pathology diagnostics. The primary objective is to create a high-performance, portable, and cost-effective imaging solution by integrating all optical components onto a single silicon chip. The research will address key technical challenges such as achieving high...

The National Cancer Institute (NCI) awarded a $400,000 Project Grant under CFDA 93.394 (Cancer Detection and Diagnosis Research) to O2M Technologies LLC to develop a Multifunctional Imager (MFI) that can simultaneously acquire tissue oxygen pressure (pO2) and pH maps using electron paramagnetic resonance imaging (EPRI) techniques. The 12-month project aims to create a 25 MT Halbach-type permanent magnet, new multi-modal transmit-receive electronics, and the integrated MFI instrument. This...

The University of Maryland, Baltimore was awarded a $1,799,728.98 Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director to purchase a state-of-the-art light sheet fluorescence microscope. The microscope will be situated in the university's established Confocal Core Facility, which will oversee use, training, and service of the instrument for nine NIH-funded research teams. Light sheet fluorescence microscopy is well-suited for...

This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $3,044,814.00 to the University of California, Irvine to develop a high-speed, multimodal deep tissue imaging system. The key products and services to be delivered under this 2-year award (9/1/2025 - 8/31/2027) include: Developing a reflection matrix-based wavefront shaping system to overcome light scattering limitations and achieve real-time,...

The National Institute of General Medical Sciences (NIGMS) awarded a $290,536 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Trestle Optics LLC, a small disadvantaged business, to develop a novel high numerical aperture catadioptric lens for ultra-broadband multimodal microscopy. This lens will enable advancements in existing nonlinear optical imaging modalities, such as three-photon excited fluorescence and third-harmonic generation, by overcoming limitations of...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will fund the development of a low-voltage, miniaturized endoscopic micro-optical coherence tomography (MOCT) system. The $405,689 award to the University of Colorado will support the validation of a low-voltage electrowetting prism scanner for high-speed MOCT imaging, as well...

This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will support the development of an ultrasonically-enhanced swept source optical coherence tomography (UESS-OCT) system for label-free, non-invasive optical imaging inside the human body. The $425,000 award to the Regents of the University of California at Riverside will fund research to utilize ultrasound waves to focus and steer light through tissue, enabling high-resolution structural and...