Project Grant R01ES029448

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to investigate the impact of prenatal exposure to copper from electronic nicotine delivery system (ENDS) aerosols on the immature neonatal pulmonary immune system and IL-10-mediated asthmatic responses. The $900,000 award, spanning from March 2025 to January 2030, will leverage in vitro and in vivo models to determine the role of IL-10 and...

This federal Project Grant award of $549,555.45 from the National Institutes of Health (NIH) Office of the Director under the Family Smoking Prevention and Tobacco Control Act Regulatory Research (CFDA 93.077) program supports research to investigate the exposure and respiratory health effects of using new and emerging electronic cigarette (e-cigarette) devices among young adults. The key products and services to be delivered through this 3-year grant, which begins on September 1, 2024, include:...

The University of Miami received a $474,999 Project Grant award from the National Science Foundation's Engineering Division (CFDA 47.041) on March 15, 2023 to characterize the physical, chemical, and toxicological properties of secondhand aerosols generated from electronic nicotine delivery systems. The University will examine secondhand aerosol size distributions, oxidative stress and cytotoxicity induction, and the roles of metals and flavorings under controlled indoor environmental conditions...

This $1,615,000 Project Grant awarded by the National Institutes of Health (NIH) Office of the Director under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) will fund a multi-year research project conducted by the Regents of the University of California, San Francisco (UCSF) to investigate the cardiovascular health effects of dual use of cigarettes and e-cigarettes. The research aims to: 1) Understand the cardiovascular impacts of dual use of...

This Project Grant award of $265,239 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to evaluate the chemical composition and toxicity of 6-methyl nicotine and nicotinamide vaping products compared to traditional nicotine e-cigarettes. Specifically, the project will: Analyze the chemical composition and metabolism of 6-methyl nicotine and nicotinamide vaping devices before and after aerosolization using mass spectrometry to...

The National Institute of Environmental Health Sciences (NIEHS) awarded a $200,230 Project Grant under the Environmental Health (CFDA 93.113) program to the University of South Carolina to study the atmospheric transformation and pulmonary toxicity of harmful cyanobacterial algae blooms. The research aims to characterize the composition and toxicity of algal aerosols and evaluate their impacts on human lung cells and immune responses. A sub-award of $XXX was provided to the University of Florida...

This $282,862 Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) supports a collaborative research effort between Oklahoma State University (OSU) and the University of California, Los Angeles (UCLA) to investigate the health risks associated with e-cigarette and cannabis aerosols, particularly those containing unregulated synthetic cooling agents. The key objectives are to: (1) quantify exposure and toxicity levels of various vaping...

This federal Project Grant award, with an ID of R01HL175602, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research (CFDA 93.837) program. The grant will fund a $1,257,395 study to quantify the long-term effects of electronic nicotine delivery system (ENDS) use on cardiovascular and pulmonary health over a 36-month period. The study will recruit 400 long-term ENDS users and 200 non-users, assessing biomarkers related to cardiovascular and...

This federal Project Grant award, funded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), will support research to assess the potential immunosuppressive effects of e-cigarette use and its impact on susceptibility to pulmonary infections. The $187,500 award to North Carolina Central University (NCCU), a Historically Black College and University (HBCU), will enable the institution to: 1) model lung cell immune dysfunction...

This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, will provide $433,950 to the University of California, Davis to study the impact of wildfire smoke exposure on lung injury in pediatric populations. The research aims to: 1) define the contribution of age on the toxicity of wood smoke particles in respiratory and alveolar epithelium, 2) define the impact of age on wood smoke particle...