Improving the timeliness and quality of care for rural lung and head-and-neck cancer patients

Active Project Grant Awarded Last action

Award ID
R01CA254730
Recipient
Awarding agency
Obligated
$4,239,342

Award facts

Assistance listing
93.393 Cancer Cause and Prevention Research
Completion date 88% complete
Originally
Funding
  • $3,677,581.00 Federal
  • $561,761.00 Non-federal
Place of performance
Aurora, CO 80045, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Improving the timeliness and quality of care for lung cancer (LC) and head and neck cancer (HNC) patients is of utmost importance because delays in treatment initiation are associated with cancer recurrence, lower survival, and poor patient outcomes (e.g., distress). Rural LC and HNC patients experience significant treatment delays. Compared to urban patients, patients in rural areas face added challenges such as needing to travel long distances to access care, having lower socio-economic status, and having less availability of cancer treatment. The objective of this study is to improve the timeliness and quality of care for LC and HNC patients who are underserved (e.g., low-income, underinsured) and from rural and frontier counties in the rocky mountain states, treated by the university of colorado health system that serves patients from colorado and wyoming and the sisters of charity of leavenworth health system that serves rural patients from colorado, utah, and montana. We will apply the cares (cancer advocacy, resources education, and support) intervention to target factors specific to rural LC and HNC patients who are underserved and factors that due to their statistical and clinical significance are associated with suboptimal initiation of treatment and poor quality of care for these patients. The hallmark of the cares intervention is implementing IT at key points during LC and HNC treatment, likely augmenting its effects on the outcomes more effectively and more efficiently than current usual care practices. Using a randomized controlled clinical trial (RCT) design, we will compare the cares intervention effects to the effects of usual care practice on the: (a) time to treatment initiation and (b) time to treatment completion. The cares intervention also targets (c) quality of care outcomes (e.g., patient communication, coordination of care, providing information to patients) and (d) patient-reported outcomes (e.g., coping, distress, quality of life). Approximately 440 LC and HNC patients will be recruited and randomly assigned to either the intervention (n=220) or to the usual care condition (n=220). We will employ intent-to-treat analyses with linear mixed models (lmms) to analyze the primary outcome of time to treatment initiation and the secondary outcomes. We predict that those who receive the cares intervention will improve in all study outcomes to a greater degree than those who received usual care. Our ultimate goal is the dissemination and implementation of the cares intervention into rural clinical practice to improve the timeliness and quality of care for rural and underserved patients and reduce disparities in LC and HNC morbidity and mortality. Thus, we will assess the pragmatic implementation and scalability of the cares intervention by evaluating the overall effectiveness of the intervention's strategies, as well as "how and why" they work in real-world practice.

Transactions

Action Federal Non-federal Date
Amendment $496,555 $0
Amendment $508,359 $0
Amendment $497,623 $0
Amendment $525,761 $0
Amendment $525,761 $0
Amendment $0 $0
Amendment $0 $0
Amendment $0 $0
Amendment $561,761 $0
Original award $561,761 $561,761

Subawards

Subrecipient Amount Awarded
Montrose Memorial Hospital Inc. Improving the Timeliness and Quality of Care for Rural Lung and Head-and-Neck Cancer Patients $79,108
Denver Research Institute $63,557
University Of Utah $44,670
Pulmonary Associates, P.C $25,080
ST. Mary's Hospital & Medical Center, Inc. -$78,145
Uch-Mhs $36,948

Quick answers

Who received award R01CA254730?

R01CA254730 was awarded to The Regents Of The University Of Colorado by National Cancer Institute (National Institutes of Health) on July 1, 2021.

How much is award R01CA254730 worth?

$4,239,342 has been obligated on R01CA254730: $3,677,581 in federal funding and $561,761 in non-federal funding.

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