This Cooperative Agreement award from the Department of Health and Human Services' Advanced Research Projects Agency for Health (ARPA-H) program, with a total funding of $8,874,227.00, aims to develop a suite of tools to enable surgeons to remove solid tumors more completely and accurately. The technologies will be initially developed and validated for breast and head and neck surgeries, but are broadly applicable to many diseases requiring surgical resection. The project involves three...
This Cooperative Agreement award, funded by the Department of Health and Human Services' Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384), aims to develop a functional prototype system called MARGINCALL that can enhance intraoperative visualization of surgical margins. The $8,945,662 project, with a performance period from Dec 2024 to Dec 2026, will enable non-destructive digital capture of histopathology, combined with a dedicated AI image analysis system, to reduce...
This $9,433,900 Cooperative Agreement awarded by the U.S. Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384) funds the development of an innovative tissue scanning and cancer detection system called "Magic Scan" by Tulane University. The key objectives are to: (1) develop an ultra-high speed, high-resolution tissue scanner that can image over 450 sq. cm of surgical tissue at 250 nm resolution...
This federal Cooperative Agreement award, issued by the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384), supports the development of a novel imaging technology called "VISION" that enables real-time, high-resolution intraoperative detection of microscopic residual cancer cells during surgical procedures. The $5,160,920 award to the Regents of the University of California, San Francisco aims to...
This Cooperative Agreement, awarded by the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) federal grant program (CFDA 93.384), provides $4,116,367 to Northeastern University and its sub-awardees University of Washington, Johns Hopkins University, and Massachusetts General Hospital. The funding supports the development of a "Fully Integrated Acousto-Optical Electronic-Photonic System for Real-Time In Vivo 3D Photoacoustic...
The University of Illinois was awarded a $13,340,331 Cooperative Agreement from the U.S. Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) federal grant program (CFDA 93.384) to develop a "MARGIN DIAGNOSTICS (MARGINDX): INTRAOPERATIVE LABEL-FREE MULTI-SCALE MULTI-MODAL OPTICAL SURGICAL IMAGING, GUIDANCE, AND DECISION-MAKING PLATFORM". This platform aims to address the challenge of high positive surgical margin rates...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...
This Project Grant award of $593,383 from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) aims to develop an AI-augmented, multimodal, label-free optical microscopy system for rapid and precise diagnosis of thyroid cancer and lymph node metastasis. The key products and services to be delivered include: A benchtop system for label-free imaging and AI-enhanced analysis of fine needle aspiration (FNA) samples to enable rapid and accurate thyroid cancer...
This $11,574,776 Cooperative Agreement awarded by the U.S. Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program aims to develop personalized radiopharmaceuticals for PET imaging-based diagnosis and targeted cancer treatment. The project will achieve this through the design of custom ligands targeted to cancer cell membrane proteins and the development of two novel devices. The first device will produce small onsite doses of...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Lightfinder Inc. aims to develop a silicon photonic optical coherence tomography (OCT) imager for pathology diagnostics. The primary objective is to create a high-performance, portable, and cost-effective imaging solution by integrating all optical components onto a single silicon chip. The research will address key technical challenges such as achieving high...