Cooperative Agreement 2538072
- This Project Grant award from the National Science Foundation (NSF), under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), provides $275,000 to Mellicell Inc. to develop an industrial-scale technology for drug development using mature human fat cells. The broader impact of this SBIR Phase I project is to enable the discovery and development of next-generation therapeutics for obesity and associated medical conditions that can be treated through weight loss. The award will...
- The National Science Foundation awarded Mechano Therapeutics LLC a $1.240 million cooperative agreement on August 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a force-stimulated delivery platform for controlled therapeutic release in joint environments. The project focuses on mechanically activated microcapsules that harness natural joint forces to deliver therapeutics with improved bioavailability and reduced systemic toxicity. Work includes...
- This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Cellecho, Inc. to develop a microchip-based technology for advanced cell engineering. The goal is to create a miniaturized liquid and cell handling platform that leverages acoustic-electric micro-vortices to precisely and sequentially deliver genetic molecules. This innovation aims to make complex cell reprogramming more...
- This National Science Foundation (NSF) Cooperative Agreement award, funded under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, will support the development and commercialization of a cost-effective peptide production platform by the small business Oakgrove Bio LLC. The $1,000,000 project aims to scale-up a recombinant technology that will dramatically decrease the cost of manufacturing peptides, which have significant potential applications ranging from antimicrobials...
- The National Science Foundation awarded a $1.25 million Cooperative Agreement to Cerflux Inc. on August 1, 2026, under the SBIR Phase II program (CFDA 47.084, NSF Technology, Innovation, and Partnerships). Cerflux will develop a scalable ex vivo testing platform built on three-dimensional tissue engineering to screen anticancer agents against solid tumors. The platform recreates key structural and biological features of tumor tissue outside the body for quantitative drug response testing....
- This $1,000,000 Cooperative Agreement award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program aims to accelerate R&D in the pharmaceutical industry through the development of streamlined machine learning algorithms for small data applications in advanced manufacturing. The project, awarded to Sunthetics Inc., seeks to save time and resources by up to 95% in lead optimization and route scouting during pre-clinical drug development by...
- The National Science Foundation awarded Asimica, Inc., a cooperative agreement totaling $1.25 million on June 15, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop microbial stem cell technology for high-yield terpene biomanufacturing. Asimica will conduct Small Business Innovation Research Phase II activities focused on overcoming product cytotoxicity in microbial biofermentations. The R&D scope includes validation in bench-top bioreactors,...
- This $256,000 National Science Foundation Project Grant under the NSF Technology, Innovation, and Partnerships program will support the development of a universal connector for high-density microfluidic chip interfaces by Neptune Fluid Flow Systems LLC. The proposed connector aims to advance lab-on-a-chip and other life science platforms by introducing a standardized microfluidic chip interface. This new interface seeks to dramatically increase diagnostic testing speeds for doctors and medical...
- The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Clemson University. The grant, awarded on August 15, 2024, with a completion date of January 31, 2026, funds the development of a novel, automated microwave system for comprehensive single-cell measurement and characterization of high-performing, stable Chinese Hamster Ovary (CHO) cells. The key products and services to be delivered through this...
- The National Science Foundation awarded Opal Therapeutics Inc. a $1.25 million cooperative agreement on August 1, 2026, to develop scalable platforms for translational research and therapeutic screening under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The project pursues three primary objectives: expanding a current biobank with increased metadata acquisition; automating culture and imaging workflows using proprietary media formulations to increase throughput and...
The National Science Foundation awarded Mellicell, Inc. a $1.25 million Cooperative Agreement on August 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to scale industrial technology for drug development. Mellicell will develop novel devices for automation and design customized protocols to expand a technology platform that enables discovery and development of next-generation therapeutics. The work focuses on scaling the technology to meet pharmaceutical industry needs for more accurate early-stage drug efficacy prediction, with potential to accelerate drug development timelines and reduce costs relative to existing methods. Mellicell will assess outcomes to determine how closely results match cellular shape, size, gene expression profile, and function of mature cells in adults, with success measured by manufacturing quality control standards and specific performance properties. Performance occurs in Watertown, Massachusetts, with a period of performance through July 31, 2028. No subawards are planned for this award.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/5/26 | ||
| Not listed | $1.3m | 7/24/26 |