Cooperative Agreement 2532118
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $450,000 project grant from the National Science Foundation's Engineering program (CFDA 47.041) awarded June 1, 2025, with completion scheduled for May 31, 2028. The award funds development of In Vitro Biomanufacturing on a Chip (IBOC), an advanced microfluidic platform designed to accelerate bioproduct development and commercialization. The IBOC system integrates nanophotonic sensors—specifically a...
- This federal Project Grant award, valued at $596,920 and provided by the National Science Foundation (NSF) Engineering program (CFDA 47.041), aims to develop a mechanism-informed AI platform to optimize biomanufacturing processes for life-saving biopharmaceuticals. Led by Northeastern University, the project will leverage emerging sensing technologies to efficiently decode the fundamental mechanisms underlying complex biomanufacturing systems. The goal is to create a flexible and robust AI-based...
- Federal Project Grant Award Summary Iowa State University received a $450,000 project grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded October 1, 2025, with completion targeted for September 30, 2027. The award funds development of a Bio-Electrocatalytic Taylor Vortex Reactor (BETR) system that integrates microbial fermentation and electrochemical hydrogenation within a...
- Federal Project Grant Summary The University of Iowa received a $1.272 million Project Grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084), awarded July 15, 2025, with completion targeted for June 30, 2028. This award supports the EPSCOR Graduate Fellowship Program (EGFP) initiative titled "Graduate Leaders in Engineering and Advanced Manufacturing (GLEAM): Enhancing Iowa's Manufacturing Capacity." The grant funds...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $552,957 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041), effective October 15, 2025, with a completion date of September 30, 2028. The award funds the development of a chip-based in vitro platform designed to study interactions between gut microbiota and brain tissue models through an artificial blood-brain barrier (BBB). This reductionist research model will...
- Federal Cooperative Agreement Summary Bluestem Biosciences Inc. received a $1.18M Small Business Innovation Research (SBIR) Phase II cooperative agreement from the National Science Foundation's Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) for the period October 1, 2025 through September 30, 2027. The company will develop an optimized yeast strain capable of producing 3-hydroxypropionic acid (3-HP) through anaerobic fermentation using whole-kernel corn feedstock. The...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $337,632 Project Grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) on July 15, 2025, with completion targeted for June 30, 2028. This Mid-Career Advancement (MCA) project develops safe and affordable alternatives to horseshoe crab blood for detecting bacterial endotoxins—harmful substances from gram-negative bacteria that pose serious...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $420,000 Project Grant from the National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) awarded August 1, 2026, with completion scheduled for July 31, 2029. The award funds research on powder-decorated laser powder bed fusion (PD-LPBF) technology designed to mitigate spattering-induced defects in laser-based metal additive manufacturing. The primary deliverable is the development...
- The National Science Foundation (NSF) awarded a $7.5 million Cooperative Agreement to Case Western Reserve University under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) beginning August 1, 2026 through July 31, 2036. This award funds the NEO-SMART (Northeast Ohio Strengthening Manufacturing for American Resilience Through Technology) Engine, a regional innovation hub designed to establish Northeast Ohio as the leading national center for advanced materials and...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $200,000 Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) effective August 15, 2025, with a completion date of July 31, 2027. The award funds a planning initiative for AI-AGARENA (AI-Ready: Cyber-Agricultural Systems Testbed), which will develop a national-scale planning roadmap and design specifications for an artificial...
The NSF RURALSTAMINA Biomanufacturing Engine, funded through the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) as a $7.5 million Cooperative Agreement awarded August 1, 2026, will develop advanced biomanufacturing capabilities in Iowa and Nebraska by transforming agricultural feedstocks into value-added bioproducts including industrial materials, food and feed ingredients, fuels, and vaccines. The initiative will bridge critical research and development gaps to transition biomanufacturing innovations from laboratory to pilot scale through three primary technical focus areas: (1) developing enabling technologies such as novel microorganisms for bioproduct manufacturing, (2) scaling biomanufacturing processes reliably for commercialization, and (3) designing and deploying sensors and artificial intelligence tools for process optimization. Administered by Iowa State University of Science and Technology and executing through July 31, 2036, the Engine brings together a coalition of more than 80 public and private partners to establish a domestic biomanufacturing base aligned with the U.S. Government's biomanufacturing strategy and supply chain resilience objectives. The award positions the Iowa-Nebraska region for national leadership in advanced bio-based manufacturing while catalyzing rural economic development and reducing dependence on foreign biomanufactured products critical to defense, health, and industrial applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $7.5m | 7/14/26 |