The National Science Foundation awarded Opera Bioscience, Inc. $275,000 under the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a low-cost bacterial production platform for manufacturing high purity recombinant proteins and growth factors. The award period runs from June 15, 2023 through May 31, 2024. Opera Bioscience will utilize this funding to demonstrate the ability of its innovative protein production platform to solve challenges in traditionally costly and...
This $2,375,361 Cooperative Agreement awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) aims to develop computational tools for designing improved protein "transporters" to enhance the efficiency of biomanufacturing processes. The 3-year project, which began on January 1, 2025, is led by Lygos, Inc., a small business in Hayward, California. The project leverages advancements in artificial intelligence and...
This National Science Foundation (NSF) Cooperative Agreement award for $1,000,000 under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to advance a recombinant technology platform that will dramatically decrease the cost of manufacturing peptides. The project, awarded to Oakgrove Bio LLC, will scale up a novel microbial cell factory approach to enable more cost-effective production and purification of peptides, which have a wide range of potential applications in...
This Project Grant award from the National Science Foundation (NSF) under its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Tectaria Bio LLC to engineer cell lines with activated proteasomes for increased biomanufacturing efficiency. The project aims to test the feasibility and application of a novel technology to significantly increase the protein production capabilities of cell lines used in the manufacture of biologics, gene therapies, and vaccines....
The National Science Foundation (NSF) awarded a $1,250,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to Micropure Genomics Inc., a minority-owned small business based in Middletown, DE. The project aims to develop an innovative platform for preparing high-quality DNA samples to support long-read sequencing technologies. The platform will automate the sample preparation process, reducing time, cost, and complexity while enhancing...
This Cooperative Agreement award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a bioprocessing system to isolate and purify therapeutic antibodies directly from cell culture. The $999,998 award to Athem LLC, a minority-owned small business, will enable scaling up a novel nanoparticle-based purification media and an automated prototype system. The goal is to simplify the manufacturing of biologics, reduce...
This $275,000 Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop improved bacterial strains for the productive secretion of difficult-to-express proteins through precision fermentation. The project seeks to identify superior bacterial protein production hosts and develop genetic tools and methodologies to convert these hosts into efficient protein...
This $275,000 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a novel platform for accelerated strain development for precision fermentation. The project aims to enhance methods for producing animal proteins through microbial fermentation, with the broader goal of reducing the environmental impact of livestock farming. Key objectives include: 1) developing a...
This SBIR Phase I project awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) will enable the generation of a massive dataset of small molecule and protein interactions to accelerate drug discovery using machine learning. The $275,000 award to Om Therapeutics Inc. aims to develop the capability to identify interactions between billions of unique small molecules and the entire human proteome. The innovation could...
This $1,248,531 Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a rapid room-temperature aerosol dehydration platform technology for stabilizing biopharmaceutical formulations. The key products to be delivered include a scalable system capable of producing stable, bioactive powders from temperature-sensitive biologics such as proteins, enzymes, viral vectors, and...