Pipp phase II: center for pandemic insights (CPI)

Active Cooperative Agreement Awarded Last action

Award ID
2412522
Recipient
Awarding agency
Obligated
$3,225,000

Award facts

Assistance listing
47.074 Biological Sciences
Completion date 31% complete
Place of performance
Davis, CA, USA

Award details come from USAspending.gov.

Description

Abstract
The center for insights into the pre-emergence phase of pandemics (CI3P) will pioneer transdisciplinary initiatives to fundamentally advance the ability to investigate and understand the pre-emergence phase of pandemics. The scale and impact of epidemics and pandemics are expected to increase substantially in future years given global trends in environmental change. Viruses that pose pandemic risk often circulate silently in wildlife, and the events that precipitate outbreaks and spillover pose formidable challenges for early detection. Innovative scientific and technological advances are urgently needed to detect the key events in the pre-emergence phase to inform mitigation of zoonotic disease outbreaks and prevent pandemics at their source. Insights into this pre-emergence phase of pandemics hold the greatest promise for reducing the frequency of epidemics and pandemics. By integrating cutting-edge technology with transdisciplinary research, CI3P will establish sensor systems that detect signals of pathogens circulating in natural reservoirs and changes in health of wildlife, and population and ecosystem measures that can provide insights into how pandemic threats emerge. Scientific and technical innovations achieved by CI3P will have broad applicability beyond animal health, public health, and wildlife conservation. By involving communities in participatory research, broadening diversity and inclusivity in science, and engaging the public in one health solutions, CI3P aims to benefit society by enhancing early detection of pandemic threats, protecting human health, preserving biodiversity, and promoting resilient ecosystems. This center will catalyze the expertise, creative strategies, and partnerships needed to tackle major challenges in pandemic research, to advance new models for predictive insights into the pre-emergence phase of pandemics. The center for insights into the pre-emergence phase of pandemics will facilitate a new paradigm for surveillance of pandemic threats, enabling characterization of key ecological, behavioral and biological events that precede pandemics. This will be achieved through transdisciplinary research and innovative technology needed to 1) inform evolutionary models of virus emergence, characterize community composition and host ecology at high-risk animal-human interfaces, and develop mechanistic models of spillover in complex environments to characterize tipping points in the pre-emergence phase of pandemics, 2) develop multimodal sensor networks for detection of pathogens, disease outbreaks, and key events, that will be deployed alongside participatory community-based research to identify social and practical barriers to large-scale use, and 3) forecast pandemic risk using a suite of machine learning algorithms developed to accommodate rare events and incorporate model-based inferences with real-time data processing for prediction. This center brings together diverse institutions and partners with the expertise needed to achieve and sustain this bold vision. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.- subawards are planned for this award.

Transactions

Action Obligated Date
Amendment $1,237,500
Amendment $0
Amendment $0
Amendment $500,000
Amendment $0
Amendment $0
Amendment $0
Original award $1,487,500

Subawards

Subrecipient Amount Awarded
Labyrinth Global Health, Inc. Scope of Work Labyrinth Global Health Subaward PI: Dr. Karen Saylors, Prime Award Co-PI Subaward Program Manager: Ms. Beth Edison Dr. Karen Saylors is a… $233,591
Zoological Society Of San Diego Scope of Work San Diego Zoo Wildlife Alliance Year 2: September 2025-August 2026 Conservation Science Wildlife Health team members at San Diego Zoo Wildlife… $80,280
Labyrinth Global Health, Inc. Scope of Work Labyrinth Global Health, Inc. Year 2: September 2025-August 2026 Dr. Karen Saylors, Co-PI, Labyrinth Global Health Dr. Karen Saylors is a social… $215,995
University Of Montana Dr. Troy Magney and his team at the University of Montana will lead tasks associated with environmental sensing and satellite remote sensing in support of… $90,007
Northeastern University Northeastern University will carry out the following tasks: (1) Lead the Strategic Direction 2 (BUILD): Technological innovations to enable preemergence… $179,031
Regents Of The University Of Michigan The University of Michigan, Ann Arbor team, led by Pei Zhang, will be responsible for the sensor integration and data transfer in the multi-level sensor… $284,722
Albert Einstein College Of Medicine Drs. Chandran and Lasso will utilize their technical expertise to help guide overall research directions of the center. They will join meetings focused on… $235,870
University Of Southern California We shall develop novel animal-human movement niche models using cutting edge machine learning approaches. We shall develop correlation analyses for the… $418,725
Colorado State University PIPP Phase II: Theme 1: Center for Transdisciplinary Innovation for Insight into Pandemic Threats $43,056

Quick answers

Who received award 2412522?

2412522 was awarded to University Of California, Davis by Division of Biological Infrastructure (National Science Foundation) on September 1, 2024.

How much is award 2412522 worth?

$3,225,000 has been obligated on 2412522.

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