Cooperative Agreement 2233590
- This Project Grant from the National Science Foundation (NSF) provides $274,999 to Robigo, Inc. for research under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The award will support development of a microbial biopesticide platform to precisely target and eliminate crop pathogens without harming beneficial microbes, pollinators, or humans. Leveraging synthetic biology, CRISPR, and data science, the company aims to engineer improvements increasing efficacy and viability...
- This $275,000 Project Grant awarded by the National Science Foundation (NSF) under the CFDA program titled "NSF Technology, Innovation, and Partnerships" aims to develop a targeted biological pesticide for controlling Pythium pathogens in hydroponic greenhouse production of leafy greens. The project will assemble a collection of diverse Pythium pathogen isolates, evaluate 10 Pseudomonad biocontrol strains, and identify the genetic basis for their host-specific killing ability to...
- This Project Grant from the National Science Foundation's Division of Industrial Innovation, totaling $250,000, supports research at Rensselaer Polytechnic Institute to develop effective and safe pesticide formulations for protecting crops from fungal diseases. Under the Engineering program (CFDA 47.041), the awardee will identify naturally produced molecules with enhanced fungicidal activity against Botrytis cinerea and Phakopsora pachyrhizi, major pathogens causing billions in annual crop...
- The National Science Foundation awarded a $300,000 EAGER grant titled "ENHANCING PLANT IMMUNITY AND GROWTH WITH CELL-PENETRATING PEPTIDES FOR ORGANIC AGRICULTURE" to The Ohio State University under the agency's Biological Sciences (CFDA 47.074) program. This two-year project aims to improve the efficiency of plant biologics, such as defense activators and biostimulants, by leveraging membrane translocation domain (MTD) technology to enhance their cellular delivery and efficacy. Key...
- Federal Project Grant Award Summary Pntbiologicals, LLC received a $175,000 Project Grant from the National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program (CFDA 10.212), awarded on September 15, 2025, with a completion date of September 14, 2027. The company is developing commercially viable biofungicide products based on naturally occurring bacteria that provide multiple agricultural benefits without the environmental and health risks...
- Federal Grant Award Summary On July 1, 2026, the National Science Foundation (NSF) awarded Rare Earth Genomics Texas, LLC a $305,000 Phase I Small Business Innovation Research (SBIR) grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to develop natural plant terpenoid-derived biopesticides. The project, titled "SAFE" (Smart-Activity-Focused-Eco), aims to create effective pest control products that degrade rapidly in the environment while...
- This $270,128 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a low-cost, field-use DNA-based rapid diagnostic device for detecting plant diseases. The project aims to create a user-friendly, battery-operated testing kit that allows farmers to quickly identify diseases like citrus greening in their fields, enabling early intervention and more sustainable farming practices. The 9-month...
- This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase II Cooperative Agreement award to Silvec Biologics Inc. provides $994,939 in funding to develop novel RNA therapies to immunize grapevines, citrus trees, and other agricultural crops against deadly bacteria, fungi, and viruses. The key objectives are to: (1) optimize small interfering RNAs (siRNAs) against the Xylella fastidiosa bacterium that causes olive quick decline syndrome, Pierce's disease in grapes,...
- Silvec Biologics Inc. was awarded a $174,964 Small Business Innovation Research (SBIR) Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture to develop a proprietary process to control fungi using RNA interference. The SBIR program aims to support scientific innovation to build a strong national economy. Under the award, Silvec will pursue four key objectives through January 2023. The company will identify small interfering RNAs compatible with...
- Invasive Species Corporation received a $181,500 Phase I Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) on September 15, 2025. The award supports the development of a commercially viable, microbe-based biological product designed to protect crops from invasive slugs and snails. The company will leverage precision fermentation and formulation platform...
SBIR PHASE II: DEVELOPMENT OF ECO-FRIENDLY PEPTIDE BIOPROTECTANT FOR DEVASTATING LATE BLIGHT CONTROL -THE BROADER IMPACT/COMMERCIAL POTENTIAL OF THIS SMALL BUSINESS INNOVATION RESEARCH (SBIR) PHASE II PROJECT WILL BE TO CONTROL SEVERAL CRITICAL PATHOGENS AND PESTS ON MULTIPLE CROPS, IN ORDER TO HELP FEED THE GROWING WORLD POPULATION MORE SUSTAINABLY. THE GLOBAL CROP PEST AND DISEASE CONTROL LANDSCAPE IS FACING BIG CHALLENGES: MANY DISEASES ARE NOT WELL CONTROLLED AND IMPORTANT CHEMICAL PESTICIDES ARE RESTRICTED OR BANNED DUE TO THEIR TOXICITY. THERE IS A CRITICAL NEED FOR NEW TYPES OF DISEASE CONTROL PRODUCTS THAT WILL BE EFFECTIVE AND WILL NOT HARM THE ENVIRONMENT OR HUMAN HEALTH. THIS PROPOSAL WILL LEAD TO THE DEVELOPMENT OF A PLATFORM THAT CAN QUICKLY GENERATE NEW PRODUCTS TO TARGET POORLY CONTROLLED PATHOGENS, MITIGATING THE DEVELOPMENT OF RESISTANT PATHOGENS. THIS SOLUTION WILL INCREASE FARMERS? PRODUCTIVITY AND REDUCE THEIR FINANCIAL LOSSES, WHILE ENSURING A MORE SECURE FOOD SUPPLY. THE PROPOSED PROJECT WILL IDENTIFY ECOLOGICALLY-SAFE PEPTIDES THAT WILL PROTECT CROPS FROM DISEASES. THE PEPTIDES WILL BE DESIGNED TO BIND TO, AND INTERFERE WITH, THE FUNCTION OF PROTEINS THAT THE DISEASE ORGANISMS PRODUCE, AND WHICH ARE ESSENTIAL TO THE DISEASE PROCESS. THE PEPTIDES WILL BE DESIGNED TO BIND ONLY TO THOSE PROTEINS, SO THEY WILL NOT HAVE OFF-TARGET EFFECTS. THE ABILITY TO RAPIDLY DESIGN AND TEST SUCH PEPTIDES WILL MAKE IT POSSIBLE TO TARGET MULTIPLE PROTEINS FROM A PATHOGEN, REDUCING THE RISK THAT THE PATHOGEN WILL DEVELOP RESISTANCE. IT WILL ALSO BE POSSIBLE TO TARGET A WIDE RANGE OF DISEASES WITH SIMILAR LIFE CYCLES, PROVIDING FARMERS WITH BROAD PROTECTION. THE PROJECT WILL CHOOSE THE OPTIMUM TARGET PROTEINS, DESIGN THE PEPTIDES, AND OPTIMIZE THE PEPTIDES TO MAXIMIZE BINDING TO THE TARGETS. THE PEPTIDES WILL BE TESTED FOR THEIR ABILITY TO PREVENT INFECTION IN THE LAB, AND THEN WILL BE PRODUCED AT A LARGER SCALE AND TESTED UNDER THE FIELD CONDITIONS. THE PEPTIDES WILL ALSO BE TESTED FOR SAFETY AS REQUIRED FOR REGULATORY APPROVAL. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $199.2k | 9/11/24 | ||
| Not listed | $6.0k | 6/11/24 | ||
| Not listed | $997.1k | 7/25/23 |