Cooperative Agreement 2028829

The National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), awarded a $400,000 Project Grant to O2M Technologies LLC to improve the image acquisition speed of their Single Point Imaging (SPI) oxygen mapping technology. SPI is a subset of the company's Pulse Electron Paramagnetic Resonance Imaging (PEPRI) method, which can generate high-resolution 3D partial oxygen pressure (pO2) maps in live tissues and tumors. The goal of this project is to...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $965,410 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Trustees of Dartmouth College. The funding will support the development of an innovative, miniaturized device called the "OXYTRACK" to enable on-site monitoring of tissue oxygen levels (pO2) in clinical settings. Key objectives include: (i) designing and...

The National Cancer Institute (NCI) awarded a $400,000 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to O2M Technologies LLC, a small for-profit corporation, to develop a Multifunctional Imager (MFI) capable of simultaneously generating 3D maps of tissue oxygen pressure (pO2) and pH. The goal of this 1-year project is to create an advanced electron paramagnetic resonance imaging (EPRI) instrument that can perform both pulse and continuous wave...

This $256,000 National Science Foundation SBIR Phase I Project Grant to Airomatix, Inc. supports the development of a portable oxygen concentrator capable of producing breathable oxygen at higher flow rates than current models. The concentrator utilizes a novel photocatalytic reaction to separate oxygen from ambient air and store it in a chemical solution. It will then release oxygen on demand through a temperature-controlled reaction. During the one-year period of performance ending March 2023,...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $578,863 to Wayne State University to develop hypoxia-sensing probes for magnetic resonance imaging (MRI) that can enable systemic delivery of europium (Eu) contrast agents. The overarching goal is to address the challenges of persistence time and relaxivity that have...

The federal Project Grant award of $318,724.00 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports the advanced development and testing of an optical probe that monitors peripheral tissue oxygenation as a marker of systemic hemodynamics in critically ill neonates. The awardee, Pendar Technologies LLC, aims to improve the sensor capabilities to enable measurements in a wider range...

This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $330,076 to Trestle Optics LLC, a small disadvantaged business located in Irvine, California, to develop an advanced photothermal microscopy platform. The objective is to create a non-destructive, high-resolution imaging system that can profile cellular metabolites, with a specific focus on monitoring the presence of pyridoxal...

RCE Technologies, Inc. was awarded a $255,892 Small Business Innovation Research Phase I Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program to develop a proof-of-concept machine learning-based diagnostic system for detecting myocardial infarction and ischemia in real-time. The system aims to provide point-of-care clinical classification for heart attack cases using a novel, portable device integrating the awardee's proprietary external...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research Federal Grant Program (CFDA 93.837), aims to develop a cost-effective Optical Sensor-Enabled Endotracheal Tube (OS-ETT) to reduce the risk and incidence of esophageal intubation and unintended extubation. The $506,500 award to Endolynx Inc. will fund a feasibility study to optimize the LED-photodiode array and signal processing algorithm for vocal cord identification,...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $374,378 Project Grant (R21EB036329) to Michigan State University to develop computational models and a miniaturized, noninvasive, wireless, luminescence-based carbon dioxide sensing wearable device. The goal is to accurately translate transcutaneous carbon dioxide (PTCCO2) measurements to arterial carbon dioxide (PACO2) levels, a vital clinical parameter, through embedded computational models. The project includes...