Block Grant R43GM084534

Partillion Bioscience Corp. was awarded a $659,037 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop reagent products enabling high-throughput screening and selection of single cells based on secreted bio-products. Under the Biomedical Research and Research Training program (CFDA 93.859), Partillion plans to transition its lab-on-a-particle technology—highlighted as a 2020 SLAS Innovation Award winner—into the first reagent product...

This National Science Foundation (NSF) Engineering grant award, under the CFD Program 47.041, provides $150,000 to the University of Georgia Research Foundation to develop novel methods for high-throughput, antibody-free cell sorting. The project, titled "EAGER: IMPRESS-U: HIGH-THROUGHPUT AGILE INTERFACES FOR CELL SORTING," aims to create an alternative, scalable approach to efficiently separate therapeutic cells from unwanted or damaged cells for biomedical applications. The...

This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $379,730 to the University of North Carolina at Chapel Hill to develop a continuous electrochemical sensor for monitoring therapeutic monoclonal antibodies, using the FDA-approved drug bevacizumab as an example. The research aims to overcome challenges in discriminating between therapeutic antibodies and human IgG in biological fluids, and in regenerating the aptamer binding site for...

The National Center for Advancing Translational Sciences (NCATS) awarded a $275,000 Project Grant (CFDA 93.350) to Nectagen Inc. to develop bioprocess-compatible, second-generation nanoclamp affinity resins for the efficient purification of plasma-based therapeutic proteins. The goal is to identify panels of nanoclamps to 5 industrially relevant plasma-based therapeutics, select lead candidates, and optimize the resins for maximum recovery and purity from plasma samples. This project aims to...

This Cooperative Agreement award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a bioprocessing system to isolate and purify therapeutic antibodies directly from cell culture. The $999,998 award to Athem LLC, a minority-owned small business, will enable scaling up a novel nanoparticle-based purification media and an automated prototype system. The goal is to simplify the manufacturing of biologics, reduce...

Federal Project Grant Award Summary Fluorofinder, LLC received a Project Grant award of $348,492 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) on July 2, 2025, with a completion date of July 1, 2026. The award funds development of the Matched Pair Tool, a digital workflow software platform designed to streamline the identification of commercially available matched antibody pairs for immunoassay...

Federal Project Grant Award Summary Nano-Beads Protein Innovations, Inc. received a $620,174 Project Grant award dated September 1, 2025, from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award supports development of NANO-AB, an innovative nanoscale biomaterial designed to advance monoclonal antibody (mAb) purification technologies. The project,...

This $255,982 National Science Foundation project grant supports the development of sustainable, cost-effective viral clearance membranes by Filtravate, Inc. to enable efficient monoclonal antibody processing. The NSF Technology, Innovation, and Partnerships program seeks technologies leading to breakthrough solutions for national challenges. Specifically, Filtravate will develop a virus filtration membrane using a synthesis process that is more sustainable and affordable than conventional...

Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...

The National Institute of General Medical Sciences (NIGMS) awarded a $356,497 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Kinetic River Corp. in Mountain View, CA. This grant, awarded on August 15, 2024, is funding the development of an ultrasensitive flow cytometry system for multiparametric analysis of therapeutic anti-aging extracellular vesicles (EVs). Extracellular vesicles show promise as biomarkers and therapeutics for a range of indications,...