Block Grant R43CA138568

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,090,971 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to develop and validate a "DEEPTOBIDX" approach for improving breast cancer diagnosis. The key products and services to be delivered include: 1) Engineering a...

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Bired Imaging Inc. to develop an innovative breast cancer screening technology. The project aims to create a rapid, efficient, and contactless screening tool that can accurately detect breast cancer, even in dense breast tissue, using infrared imaging and physics-based AI algorithms. The goal is to improve early detection of...

The National Science Foundation awarded Malcova Inc. $1,000,000 under the Technology, Innovation, and Partnerships federal grant program (CFDA 47.084) to develop a novel non-planar spectral breast computed tomography device. Malcova will use the one-year project grant term from May 1, 2023 to April 30, 2024 to further the device's design, build a working prototype, and conduct validation testing using anthropomorphic phantoms. The non-invasive breast CT device employs a new scanning method and...

The National Cancer Institute (NCI) awarded a $400,000 Project Grant under CFDA 93.394 (Cancer Detection and Diagnosis Research) to O2M Technologies LLC to develop a Multifunctional Imager (MFI) that can simultaneously acquire tissue oxygen pressure (pO2) and pH maps using electron paramagnetic resonance imaging (EPRI) techniques. The 12-month project aims to create a 25 MT Halbach-type permanent magnet, new multi-modal transmit-receive electronics, and the integrated MFI instrument. This...

The University of Washington was awarded a $2,758,909 Cooperative Agreement under the National Institute of Biomedical Imaging and Bioenginering's (NIBIB) Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The project, titled "Integrated PET+DBT for Optimization of Breast Cancer Therapy," aims to develop an innovative dual-mode breast cancer scanner combining positron emission tomography (PET) and x-ray tomosynthesis (XT). This...

The federal Project Grant award of $246,124 from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) supports the development of a personalized, patient-centered "BREATHS" system to improve the consistency of deep inspiration breath holds (DIBH) during radiation therapy for breast cancer patients. The project aims to refine and evaluate the BREATHS system, which uses video display glasses and a respiratory sensor belt to provide real-time...

This Project Grant award, totaling $651,514 and provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 Arthritis, Musculoskeletal and Skin Diseases Research, aims to evaluate the use of digital tomosynthesis (DWT) imaging of the wrist to monitor bone quality changes in breast cancer patients receiving aromatase inhibitor therapy. The key objectives are to: 1) assess how bone quality metrics derived from DWT images change over time in...

The National Cancer Institute (NCI) awarded a $155,028 Project Grant (CFDA 93.394 - Cancer Detection and Diagnosis Research) to the Georgia Tech Research Corporation to develop an advanced 3D auxetic biodegradable implant for large volume breast reconstruction. The key products and services to be delivered under this 2-year grant include: Characterization and scaling up of a novel auxetic (re-entrant) architectural design for biodegradable breast implants to enhance flexibility, durability,...

This federal Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) provides $1,043,109 to Isono Health, Inc. to develop and validate artificial intelligence (AI) models for its ATUSA 3D breast ultrasound imaging platform. The goal is to create lesion classification, lesion segmentation, and breast density calculator AI models to improve the ATUSA system's ability to accurately identify and diagnose breast cancer at an...

This $446,127 National Science Foundation (NSF) Faculty Early Career Development (CAREER) Program grant awarded to Wayne State University supports the development of a novel optical imaging technology called Photoacoustic-Brillouin Microscopy (PABM). This non-contact, non-invasive approach will enable high-resolution, 3D quantification of the mechanical properties of cancer cells and their microenvironment. In addition to directly measuring tissue stiffness, the PABM system will also provide...