Block Grant R21MH074008

This Project Grant from the National Institutes of Health National Cancer Institute totaling $1,170,174 was awarded to Trevarx Biomedical, Inc. on April 1, 2021 with a completion date of March 31, 2022. The grant supports development of an optimized synthesis platform for the radiotracer [18F]FTT under the Cancer Treatment Research program (CFDA 93.395). Specifically, the funding will allow Trevarx Biomedical and the University of Pennsylvania to determine the best method for synthesizing...

The National Science Foundation awarded Theracea Pharma LC a $256,000 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop bioconjugation and preparation of fluorine-18 biomolecules for positron emission tomography (PET) imaging. The grant period runs from August 15, 2021 through July 31, 2023 in Tucson, Arizona. Under this award, Theracea Pharma LC will work to advance science and engineering research and innovation leading to breakthrough...

Federal Project Grant Award Summary Synvest Imaging Inc. received a $499,844 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on September 20, 2025, with completion scheduled for September 19, 2026. The award supports the development of scalable Current Good Manufacturing Practice (cGMP) production methods for 18F-labeled synaptic vesicle glycoprotein 2A (SV2A) positron emission tomography (PET) tracers, specifically 18F-SYNVEST-1 and...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $426,250 to Wake Forest University Health Sciences to develop and evaluate a novel positron emission tomography (PET) radiotracer, [11C]TM-N1324, to measure levels of the G-protein coupled receptor GPR39 in rodent models and postmortem human brain tissues of Alzheimer's disease (AD). The project aims to establish the utility of this PET imaging approach for quantifying GPR39, which is implicated...

This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides funding of $799,962 to Tripill Biotechnology, Corp. to develop radiolabeled PSMA agents with low salivary gland uptake for improved prostate cancer imaging and therapy. The key products and services to be delivered include: Constructing PSMA derivative compounds, such as NOTA-UNC-PSMA2, that can selectively reduce salivary gland uptake while maintaining high tumor uptake in prostate...

Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded $618,670 to The Washington University under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) on August 1, 2025, with completion targeted for July 31, 2028. This Project Grant supports the development of novel positron emission tomography (PET) radiotracers targeting the tandem pore domain halothane-inhibited K+ channel 1...

Federal Project Grant Award Summary Emory University received a $402,401 Project Grant award from the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394), effective May 6, 2026, with a completion date of April 30, 2028. The award supports the development of an 18F-labeled positron emission tomography (PET) imaging agent capable of detecting and measuring isocitrate dehydrogenase 1 mutant (IDH1-R132H) expression in gliomas. This exploratory...

This Project Grant award, provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), will support Professor Trevor Hayton of the University of California, Santa Barbara (UCSB) in the development of triphenylmethyl (trityl) group-based small molecule delivery agents, magnetic materials, and metal nanoclusters. The $580,406 award over 3 years (9/1/2024 - 8/31/2027) will enable Professor Hayton to explore new synthetic methodologies,...

The Rochester Institute of Technology (RIT) was awarded a $250,000 Project Grant from the National Science Foundation Division of Chemistry to develop the novel NMR-PNS technique for determining macromolecular and liquid structure. Under the two-year award running from September 2021 through August 2023, RIT will combine nuclear magnetic resonance and neutron scattering to advance understanding of major problems in the mathematical and physical sciences. Specifically, RIT aims to promote...

The National Science Foundation (NSF) Directorate for Engineering awarded a $150,000 Project Grant to the University of Alabama in Huntsville (UAH) to support the development of new magnetic particle imaging tracers. The goal is to create superparamagnetic iron oxide nanoparticle clusters with controlled properties that can be used to improve magnetic particle imaging, a non-invasive medical imaging technique similar to MRI. Key objectives include designing and synthesizing poly(amino acid)...