Purchase Order VA526D95022

The Department of Health and Human Services' National Institutes of Health National Institute of Child Health and Human Development awarded a $121,347 firm fixed price purchase order to Cyagen Biomodels LLC of Santa Clara, California. The contract is for the generation of conditional knock-in and knock-out mouse models to support the agency's research focusing on the development of the mammalian hematopoietic system and study of signal transduction molecules and pathways that regulate T...

This is a $249,334 firm fixed-price purchase order awarded by the National Institute on Aging (NIA) to Scantox Neuro GMBH, a for-profit organization based in Austria. The contract supports pharmacodynamic and tolerability studies of candidate Alzheimer's disease (AD) drugs using a transgenic AD mouse model. This work builds on NIA's ongoing efforts under the Drug Repurposing for Effective Alzheimer's Medicines (DREAM) and Experimental Validation of Candidate Alzheimer's Disease Treatments...

This firm-fixed-price purchase order contract, valued at $13,594.30, was awarded by the National Institute on Aging (NIA), a civilian agency within the U.S. Department of Health and Human Services, to Cyagen Biomodels LLC, a for-profit biotechnology company located in Santa Clara, California. The contract is for the generation of a TBX3 conditional knockout mouse strain to support biomedical research. No small business set-aside was used for this award. Cyagen Biomodels LLC specializes in...

This is a $35,160 firm-fixed-price purchase order awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the U.S. Department of Health and Human Services' National Institutes of Health (NIH), to Ozgene PTY LTD, an Australian company, for the generation of a THRB-Cre-ERT2 knock-in mouse model. The work involves designing and constructing a targeting vector, selecting recombinant embryonic stem cell clones, and generating founder mice carrying the...

This federal contract award to Ozgene PTY LTD, an Australian company, is for the delivery of genetically modified mice and related services to support biomedical research at various institutes and centers within the U.S. Department of Health and Human Services' National Institutes of Health (NIH). The specific services provided under this $5,970.00 firm fixed price delivery order contract include gene targeting vector design and creation, mouse embryonic stem cell generation, blastocyst...

The National Institutes of Health National Institute on Aging awarded a $7,345,832 delivery order to Charles River Laboratories, Inc. to develop and maintain a multigenotypic aged mouse colony. This delivery order was issued against the company's existing indefinite delivery vehicle with the National Institute on Aging to supply aged rodent models supporting studies of aging processes. No set-aside designation was applied to this award. Charles River will utilize its expertise in disease model...

This federal contract award is to Ozgene PTY LTD, an Australian company that provides genetically modified mice and related services to support biomedical research. The award is a $57,600.00 firm-fixed-price delivery order issued by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services. The contract is for the generation of a non-conditional genetically modified mouse strain,...

This is a $249,167.58 firm fixed price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency under the National Institutes of Health (NIH), to Gempharmatech LLC, a foreign-owned for-profit biotech company. The contract is for the development of humanized mouse models for nicotinamide N-methyltransferase (NNMT) and sulfotransferase (SULT1A1) using CRISPR knock-in technology. The contractor will conduct biochemical testing of inhibitors and...

This contract was awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. Department of Health and Human Services' National Institutes of Health (NIH), to Ozgene Pty Ltd, an Australian company. The contract, valued at $67,700.00, is for the provision of genetically modified mice and rats to support biomedical research. The contract does not have a set-aside designation. Ozgene, the prime contractor, will provide gene targeting vectors, mouse backcrossing,...

This federal contract award from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services, was issued to the prime contractor Ozgene Pty Ltd, an Australian company that provides genetically modified mice and related services to support biomedical research. The $4,850.10 fixed price award is for a project titled "AMBIS 1736053 PROJECT NO. 1551.6 BREEDING TO GENERATE A...