Purchase Order HHSN311201700071P

This federal contract award to QPS LLC, a minority-owned limited liability company, is for the provision of rodent pharmacokinetic (PK) testing services to support the National Institute of Neurological Disorders and Stroke's (NINDS) Helping to End Addiction Long-term (HEAL) initiative. The $98,000.00 firm-fixed-price purchase order contract has a period of performance through September 22, 2025. The contract was competitively awarded and does not have a set-aside designation. The services to be...

This is a delivery order awarded by the National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) to Societal CDMO San Diego, LLC, a small disadvantaged business contract development and manufacturing organization (CDMO). The $494,300 firm-fixed-price task order is for dosage form development, manufacture, and stability studies of the investigational compound metarrestin (ML246) under the larger "CRO Support for NCATS Drug Product Development,...

The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $1,027,022.00 cost-plus-fixed-fee delivery order contract to Sri International, a non-profit research institute, for non-clinical safety assessment of the drug candidate VK4-116 to support the treatment of severe pain disorders in human patients. This contract is part of the NCATS "CRO Support for NCATS In Vitro and In Vivo Toxicology Studies"...

This is a $129,586.25 firm fixed-price purchase order contract awarded by the National Institute of Neurological Disorders and Stroke (NINDS), a civilian agency, to Melior Discovery Inc. to provide continuous rodent and non-rodent pharmacokinetic assessment services. The contract was awarded under the NINDS Division Translational Research - Continuous Rodent and Non-Rodent Pharmacokinetic (PK) Assessments solicitation, which sought commercial sources with the capability to conduct routine rodent...

The Department of Health and Human Services National Institutes of Health National Institute of Neurological Disorders and Stroke awarded a $6,338 firm fixed price purchase order to Cyprotex US LLC for ADME-TOX screening services in support of preliminary safety assessment of a new lead candidate for the agency's HER3 receptor project. Work will be performed by Cyprotex US LLC Division in Watertown, Massachusetts over a one year period concluding on August 30, 2024. The award was made using...

This is a cost-plus-fixed-fee Delivery Order awarded by the National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke to PPD Development LP, a global contract research organization (CRO). The $2,104,350.00 task order is for protocol development, database build, and bioanalytical methods development in support of a Phase I clinical trial for the neurotherapeutic drug candidate AZD4041. The award is part of a larger Indefinite Delivery/Indefinite Quantity...

This firm fixed price purchase order contract was awarded by the National Institute on Aging, a civilian agency within the U.S. Department of Health and Human Services, to Case Western Reserve University's Office of Research Administration Division (doing business as University Hospitals of Cleveland). The $20,900.00 contract provides for laboratory services to evaluate the effects of the drug exenatide on mitochondrial function in a Parkinson's disease mouse model. The contract has an...

This is a $249,334 firm fixed-price purchase order awarded by the National Institute on Aging (NIA) to Scantox Neuro GMBH, a for-profit organization based in Austria. The contract supports pharmacodynamic and tolerability studies of candidate Alzheimer's disease (AD) drugs using a transgenic AD mouse model. This work builds on NIA's ongoing efforts under the Drug Repurposing for Effective Alzheimer's Medicines (DREAM) and Experimental Validation of Candidate Alzheimer's Disease Treatments...

This is a purchase order awarded by the National Heart Lung and Blood Institute (NHLBI), a civilian agency within the Department of Health and Human Services, to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The $6,870 firm-fixed-price contract is for laboratory support services to analyze human cerebrospinal fluid and plasma samples from a National Institute on Aging (NIA) clinical trial evaluating the use of...

This is a $55,260 federal contract awarded by the National Center for Advancing Translational Sciences (NCATS), a center within the National Institutes of Health (NIH), to Charles River Laboratories, Inc. The contract is for the testing of 10 small molecule compounds in rat pharmacokinetic experiments. The original solicitation was a Small Business Sources Sought notice seeking qualified small businesses capable of performing this type of specialized preclinical research. The contract does not...