Safety evaluation of YC1 in HSULT1A1 and MSULT1A1 mice.
Ended Purchase Order Awarded
- Contract number
- 75N95025P00413
- Awardee
-
Gempharmatech LLC UEI H42SCKKGRTU3
- Awarding agency
-
National Institute on Drug Abuse
National Institutes of Health, Department of Health and Human Services
- Obligated
- $58,936
Award facts
- Opportunity
-
- Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice Pre-Solicitation · 75N95025Q00237 · Posted Aug 12, 2025
- Contract value 100% obligated
- $58,936.00 Current and potential, with all options
- Completion date 100% complete
- Current and potential, with all options
- NAICS code
- 541380 Testing Laboratories and Services
- PSC
- Q301 Reference Laboratory Testing
- Set-aside
- No set-aside
- Competition
- Not Competed under SAP · 1 offer Simplified Acquisition
- Pricing
- Firm Fixed Price
- Place of performance
- San Diego, CA 92121, USA
Award details come from SAM.gov/FPDS.
About this award
This contract award to Gempharmatech LLC, a foreign-owned biotechnology company in San Diego, California, is for a $58,936 fixed-price purchase order to evaluate the safety of the compound YC1 in mice with humanized SULT1A1 proteins versus standard mouse SULT1A1 proteins. The contract was awarded by the National Center for Advancing Translational Sciences (NCATS), which operates under the National Institutes of Health within the Department of Health and Human Services.
The objective is to establish the therapeutic window for YC1, which has a unique mechanism of cytotoxicity against cancer cells expressing SULT1A1. This non-competitive, sole-source award to Gempharmatech is based on the company's exclusive capability to produce the required humanized SULT1A1 mouse models essential for the comparative toxicology study. The 6-month research effort involves administering ascending doses of YC1 to 24 male mice across four treatment groups, followed by comprehensive monitoring, blood analysis, and histopathology.
Quick answers
Who was awarded contract 75N95025P00413?
75N95025P00413 was awarded to Gempharmatech LLC by National Institute on Drug Abuse (National Institutes of Health) on September 24, 2025.
How much is contract 75N95025P00413 worth?
The government has obligated $58,936 on 75N95025P00413.
Was contract 75N95025P00413 competed?
The extent of competition for 75N95025P00413 was not competed under sap. The government received 1 offer.
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