Purchase Order 75N95025P00412
- Not listed
- This is a $249,500 firm fixed-price purchase order awarded by the Department of Health and Human Services' National Institutes of Health National Institute on Drug Abuse to Chemogenics Biopharma, LLC, a small business. The contract is for synthesis and bioanalytical analysis support services related to the therapeutic areas of the microbiome, neurodegeneration, and addiction. The services will augment existing medicinal chemistry campaigns within the National Center for Advancing Translational...
- This is a $24,900.00 firm fixed price purchase order awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute on Drug Abuse to Chemogenics Biopharma, LLC, a for-profit limited liability company and sole proprietorship, on July 23, 2019. The contract has a completion date of September 30, 2019 and does not have a set-aside designation. Chemogenics Biopharma, LLC is a leading company in preclinical drug discovery and has been awarded several...
- The federal contract award HHSN271201500037A, valued at $498,000.00, was issued by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services (HHS). The contract was awarded to Chemdiv, Inc., a for-profit organization based in San Diego, California, to provide small molecule compounds to support the National Center for Advancing Translational Sciences (NCATS) Pharmacologically Active Chemical Toolbox...
- This federal contract award, with the ID HHSN271201500620P, was issued by the National Institute on Drug Abuse (NIDA), a civilian agency within the U.S. government. The contract, with a ceiling value of $148,905.00, was awarded to Chembridge Corp, a for-profit organization based in San Diego, California. The contract is for the Small Molecules for NCATS Pharmacologically Active Chemical Toolbox (NPACT) program, which is a purchase order with a firm fixed price. The contract does not have a...
- The National Institutes of Health National Institute on Drug Abuse awarded a $288,375 firm fixed price purchase order to Curia Global Inc., doing business as Amri, to provide non-GMP synthesis of up to 100 ligands that bind the KIAA0203 protein. Under the terms of the contract, Amri will synthesize the ligands in 2-10 milligram quantities over a one-year period of performance. Amri must dedicate two full-time scientists and one part-time scientist at 25% effort to update progress. There is no...
- The National Institutes of Health's National Center for Advancing Translational Sciences awarded a $99,000 firm fixed price purchase order to Targetmol Chemicals Inc. to synthesize analogs of repsox and intermediates from two ongoing medicinal chemistry projects. Over a six-month period after receipt of order, Targetmol will synthesize the requested compounds and deliver milligram to gram quantities to NCATS along with electronic progress reports, analytical data including LCMS and 1H NMR, and...
- <p>The U.S. National Institute on Drug Abuse (NIDA), a civilian federal agency, awarded a $452,500.00 firm fixed-price purchase order contract to Chemroutes Corporation, a foreign-owned for-profit organization, for the Small Molecules for NCATS Pharmacologically Active Chemical Toolbox (NPACT) program. The contract has an ultimate completion date of April 30, 2016 and was awarded on December 23, 2015. This contract was not set aside for any particular business type.</p>
- The Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences awarded a $19,800 firm fixed price purchase order to Karebay Biochem Inc., a for-profit small business, to synthesize 200 grams of compound NCGC00413972. This order supports NIH's biomedical research programs, particularly in the areas of drug discovery and infectious disease. Karebay Biochem has received multiple prior purchase orders from NIH entities to...
- The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) awarded a $30,035 firm fixed price purchase order to Medchemexpress LLC of Princeton, New Jersey for the synthesis of synthetic compounds to support NCATS. Under the terms of the award, Medchemexpress will provide synthetic compound synthesis services to NCATS by November 11, 2022. No set-aside provisions were applied to this procurement. As the lead institute for NIH's translational...
- This is a firm fixed-price purchase order awarded by the National Institute on Drug Abuse (NIDA), on behalf of the National Institute of Neurological Disorders and Stroke (NINDS), to Curia Global Inc. (doing business as Amri) for the non-GMP synthesis of up to 100 compounds in 2-10 milligram quantities. The purpose is to identify molecules that bind the KIAA0203 protein, which could potentially lead to the development of a new Alzheimer's drug. The contract has a period of performance from...
The National Institute on Drug Abuse awarded a $101,000 firm fixed-price purchase order to Chemogenics Biopharma, LLC on September 16, 2025, for synthesis and bioanalytical analysis services supporting the National Center for Advancing Translational Sciences (NCATS) Early Translational Branch Chemistry Program. The contract, which extends through July 15, 2026, is performable in Durham, North Carolina. This procurement does not utilize a small business set-aside designation. The work involves custom synthesis of small molecule inhibitors targeting physiological methyltransferases implicated in disease, including delivery of 100 grams each of two specified chemical compounds with greater than 95% purity and optical purity exceeding 98%, accompanied by comprehensive spectroscopic characterization and analytical data. In addition to chemical synthesis, the contract encompasses pharmacokinetic analysis of small molecule compounds using mouse models across multiple routes of administration and tissue types to generate exposure data supporting compound selection for proof-of-concept studies. Chemogenics Biopharma was selected as the sole-source contractor based on its demonstrated prior performance on similar NCATS projects. The company, registered in the System for Award Management since April 2011, specializes in custom chemical synthesis and bioanalytical services for pharmaceutical and medical research institutions, with previous federal contract experience totaling approximately $513,040 across multiple NIH agencies.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Synthesis of HNMT, NNMT intermediates and PK | 75N95025Q00236 | Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse | Pre-Solicitation 1/1 | 8/12/25, 6:48 AM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $101.0k | 9/16/25 |