Generation of two (2) lines of mice in which the ctcf gene is modified by crispr gene editing to contain either (1) an R448Q mutation; (2) a GRP>AAA mutation in A.A. 662-664. Please see attached slide…

Ended Purchase Order Awarded Last action

Contract number
75N93023P01167
Awardee
Awarding agency
Obligated
$60,000

Award facts

Contract value 100% obligated
$60,000.00 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
NAICS code
112990 All Other Animal Production
Set-aside
No set-aside
Competition
Not Competed under SAP · 1 offer Simplified Acquisition
Pricing
Firm Fixed Price
Place of performance
Worcester, MA 01605, USA

Award details come from SAM.gov/FPDS.

About this award

This firm fixed price purchase order, valued at $60,000, was awarded by the National Institutes of Health's National Institute of Allergy and Infectious Diseases to Leveragen Inc. of Worcester, Massachusetts. Under this contract, Leveragen will generate two lines of mice with specific CRISPR gene edits to the CTCF gene, containing either an R448Q mutation or a GRP>AAA mutation in amino acids 662-664. This work directly continues the solicitation to develop broadly neutralizing nanobodies targeting the CD4 binding site of HIV-1 through immunization of alpacas with HIV-1 Env trimers, by providing the genetically modified mice required for further study as described in the attached slide deck. Leveragen will deliver the mice lines over a one year period beginning in late August 2023.

Description

Generation of two (2) lines of mice in which the ctcf gene is modified by crispr gene editing to contain either (1) an R448Q mutation; (2) a GRP>AAA mutation in A.A. 662-664. Please see attached slide deck for design strategies. Complete service F

Quick answers

Who was awarded contract 75N93023P01167?

75N93023P01167 was awarded to Leveragen Inc. by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on August 30, 2023.

How much is contract 75N93023P01167 worth?

The government has obligated $60,000 on 75N93023P01167.

Was contract 75N93023P01167 competed?

The extent of competition for 75N93023P01167 was not competed under sap. The government received 1 offer.

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