Purchase Order 75N93023P01167
- Not listed
- This is a firm-fixed-price purchase order contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to Ingenious Targeting Laboratory Inc. The contract is valued at $31,245.00 and has a completion date of December 31, 2013. The contract is for the provision of ROSA26 knock-in mice, which are genetically modified mouse models used in biomedical research. The contract was set aside for small businesses, and Ingenious...
- The Department of Health and Human Services National Institutes of Health National Heart Lung and Blood Institute awarded a $996,710 firm fixed price purchase order to Lumicks USA Inc. to generate HBB, HBBS, and HBBE knock-in mice. The solicitation sought a contractor capable of generating transgenic and knock-in mouse models using CRISPR/Cas9 or other genome editing technologies for biomedical research purposes. No set-aside designation or incumbent contractor was specified. Lumicks will...
- This federal contract award is for the provision of live animals, specifically genetically modified mice, to support biomedical research. The prime contractor, Ozgene PTY LTD, an Australian company, is providing gene targeting vectors, mouse backcrossing, and the creation of gene knockout and gene knock-in mice to various agencies within the U.S. Department of Health and Human Service's National Institutes of Health (NIH). The contract, with a ceiling value of $5,971.00, is a firm fixed-price...
- This is a $249,167.58 firm fixed price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency under the National Institutes of Health (NIH), to Gempharmatech LLC, a foreign-owned for-profit biotech company. The contract is for the development of humanized mouse models for nicotinamide N-methyltransferase (NNMT) and sulfotransferase (SULT1A1) using CRISPR knock-in technology. The contractor will conduct biochemical testing of inhibitors and...
- This federal contract award is for a delivery order issued by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services. The prime contractor is Ozgene PTY LTD, an Australian company that provides genetically modified mice and related services to support biomedical research. The award, valued at $7,286.00, is for additional breeding and other services to support gene targeting,...
- The National Institutes of Health National Institute of Allergy and Infectious Diseases (NIH NIAID) awarded a $59,541 firm fixed price purchase order to Genscript USA Inc. to provide customized antibody synthesis, expression, purification, and plasmid preparations in support of the Laboratory of Malaria Immunology and Vaccinology's (LMIV) malaria vaccine research. Per the original solicitation, LMIV requires custom monoclonal antibodies that can label and sort immune cell subsets in its colony...
- This is a firm fixed price purchase order contract awarded by the National Institute on Aging (NIA), a civilian agency within the National Institutes of Health (NIH), to Gempharmatech LLC, a foreign-owned for-profit biotechnology company. The contract is for the delivery of specialized Kremen1-flox mice, which are a type of knockout mouse model, to support preclinical drug discovery and development research. The contract has a ceiling value of $13,509.55 and a completion date of November 19,...
- This federal contract award from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services, was issued to the prime contractor Ozgene Pty Ltd, an Australian company that provides genetically modified mice and related services to support biomedical research. The $4,850.10 fixed price award is for a project titled "AMBIS 1736053 PROJECT NO. 1551.6 BREEDING TO GENERATE A...
- The Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases awarded a $25,000 firm fixed price purchase order to Cyagen Biomodels LLC for a project to conditionally knockout mouse WNK1 and STK10 genes using CRISPR/Cas9 technology. Work will be performed by Cyagen Biomodels LLC Division in Santa Clara, California over a period of four months concluding in late December 2023. The award was made to the prime contractor Cyagen...
- This is a $4,565 firm fixed price purchase order awarded to Envigo Bioproducts Inc. by the National Institute of Allergy and Infectious Diseases, a component of the U.S. Department of Health and Human Services. The contract is for the provision of 30 nude mice for antibody production. No set-aside designation was used. Envigo Bioproducts Inc. is a discovery and development contract research organization that has previously provided specialized biomedical products and services, including mice, to...
This firm fixed price purchase order, valued at $60,000, was awarded by the National Institutes of Health's National Institute of Allergy and Infectious Diseases to Leveragen Inc. of Worcester, Massachusetts. Under this contract, Leveragen will generate two lines of mice with specific CRISPR gene edits to the CTCF gene, containing either an R448Q mutation or a GRP>AAA mutation in amino acids 662-664. This work directly continues the solicitation to develop broadly neutralizing nanobodies targeting the CD4 binding site of HIV-1 through immunization of alpacas with HIV-1 Env trimers, by providing the genetically modified mice required for further study as described in the attached slide deck. Leveragen will deliver the mice lines over a one year period beginning in late August 2023.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Immunization of Alpacas with HIV-1 Env Trimers to Develop Broadly Neutralizing Nanobodies Targeting CD4 Binding Site | NOI-NIAID-23-2182229 | Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases | Pre-Solicitation 1/1 | 8/8/23, 7:23 PM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $60.0k | 8/29/23 |