Central nervous system (CNS)-3D brain organoids neuropharmacological analysis EO 14398

Active Purchase Order Awarded Last action

Contract number
75F40126P00150
Awardee
Awarding agency
Obligated
$143,021

Award facts

Opportunity
Contract value 100% obligated
$143,020.98 Current and potential, with all options
Completion date 35% complete
Current and potential, with all options
NAICS code
541380 Testing Laboratories and Services
PSC
B537 Special Studies/Analysis- Medical/Health
Set-aside
No set-aside
Competition
Not Competed under SAP · 1 offer Simplified Acquisition
Pricing
Firm Fixed Price
Place of performance
Metairie, LA 70006, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

About this award

The Food and Drug Administration awarded a purchase order to 28Bio, Inc. for Central Nervous System 3D brain organoids neuropharmacological analysis valued at $143,020.98, with an award date of August 1, 2026. Performance is located in Metairie, Louisiana and extends through April 30, 2027. The order calls for functional examination of neuromodulatory effects of a marketed small molecule drug using human CNS 3D brain organoids, including characterization of acute and chronic effects through calcium flux measurements, evaluation of 5-HT5A receptor involvement via co-treatment studies, viability assessments via LDH assays, and RNA sequencing to assess transcriptional changes following chronic drug exposure. Testing uses 28Bio organoids at 10 weeks of differentiation across 10 treatment groups with 32 organoids per group. Deliverables include final study design within one month of award, acute and chronic neuromodulatory effects data by January 31, 2027, and transcriptomic data by March 31, 2027. The order originated from a pre-solicitation notice posted April 24, 2026.

Quick answers

Who was awarded contract 75F40126P00150?

75F40126P00150 was awarded to 28Bio, Inc. by Food and Drug Administration (Department of Health and Human Services) on August 1, 2026.

How much is contract 75F40126P00150 worth?

The government has obligated $143,021 on 75F40126P00150.

Was contract 75F40126P00150 competed?

The extent of competition for 75F40126P00150 was not competed under sap. The government received 1 offer.

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