Purchase Order 75F40120P00191

The Department of Health and Human Services Food and Drug Administration awarded a $56,042.50 firm fixed price purchase order to Firalis Molecular Precision SA for MIRNA whole transcriptome assay services in human plasma samples. Firalis, doing business as Firalis and a subsidiary of Firalis, will perform the requested microRNA whole transcriptome assays in human plasma samples to support FDA programs from July 2024 through November 2024. No major subcontractors or set aside designations were...

The Department of Health and Human Services' National Institutes of Health's National Center for Advancing Translational Sciences awarded a $13,474 purchase order to Horizon Discovery Biosciences Limited of Great Britain. Under the firm fixed price contract, Horizon Discovery will provide ON-TARGETPLUS MOUSE AAK1 small interfering RNA SMARTPOOL consisting of 50 nanomoles of the described product. Place of performance will be Great Britain, with work occurring between September 5 and November...

This is a $35,600 firm fixed price purchase order contract awarded by the National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) to Pharmaron, Inc., a minority-owned for-profit organization, to conduct a mouse study evaluating NNMT inhibitors in high grade serous ovarian cancer. The work, which has a 12-month period of performance, involves formulating compounds, developing a mouse model, conducting efficacy studies, and analyzing samples. No set-aside...

The Department of Health and Human Services Food and Drug Administration awarded a firm fixed price purchase order to the University of Texas Southwestern Medical Center, a non-profit educational institution, for next-generation sequencing analysis of microRNA expression on commercially available human hepatic cell lines and bioinformatic data analysis to identify microRNAs associated with drug-induced liver injury. The contract, which does not have a set-aside designation, has a potential value...

The Department of Health and Human Services Food and Drug Administration (HHS FDA) awarded a $16,514 purchase order to Arraystar Inc. to provide exosome miRNA profiling and sequencing services. The firm fixed price contract has a period of performance from September 19, 2023 through April 25, 2024 and will be performed in Silver Spring, Maryland. Arraystar will deliver the requested exosome profiling and sequencing services to support HHS FDA programs. No subcontractors or set aside designations...

This is a firm fixed-price purchase order contract awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases to Mirimus, Inc., a self-certified small disadvantaged business. The $17,147.50 contract is for the delivery of custom vector expressions to support biomedical research. Mirimus is a provider of customized mouse models and reagents, specializing in reversible gene silencing technologies. In addition to...

The Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences (NIH NCATS) awarded a $122,612.40 firm fixed-price purchase order to Horizon Discovery Biosciences LIMITED, a foreign-owned for-profit manufacturer, for 14 Mouse ON-TARGET plus small interfering RNA (siRNA) libraries. This non-competitive, brand-name acquisition was conducted under simplified acquisition procedures without any small business set-aside. The purchase...

This is a $249,167.58 firm fixed price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency under the National Institutes of Health (NIH), to Gempharmatech LLC, a foreign-owned for-profit biotech company. The contract is for the development of humanized mouse models for nicotinamide N-methyltransferase (NNMT) and sulfotransferase (SULT1A1) using CRISPR knock-in technology. The contractor will conduct biochemical testing of inhibitors and...

This federal contract award, valued at $44,208.00, was issued by the National Cancer Institute (NCI) to Novogene Corp Inc., a minority-owned small business. The contract is for services to identify long non-coding RNA (lncRNA) and microRNA (miRNA) profiles that are regulated in a radiation-responsive manner in human endothelial cells. The work was awarded through a sole-source acquisition under simplified procedures for commercial items. Novogene was selected due to its prior experience and...

The Department of Health and Human Services National Institutes of Health National Human Genome Research Institute awarded a firm fixed price purchase order valued at approximately $668,710 to Norgen Biotek Corp. of Ottawa, Canada. Under the terms of the contract, Norgen Biotek will extract and isolate intact RNA exosomes from plasma samples to support an unspecified clinical study being conducted by the National Heart, Lung and Blood Institute. The original solicitation sought proposals for...