Production of GLP erythromer for IND enabling animal studies

Ended Other Transaction Agreement Awarded

Contract number
HR00112590241
Awardee
Awarding agency
Obligated
$1,799,993

Award facts

Contract value 100% obligated
$1,799,993.00 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
NAICS code
Not on record
PSC
AC15 National Defense R&D Svcs; Department Of Defense - Military; R&D Facilities & Maj Equip
Set-aside
No set-aside
Competition
Competed Broad Agency Announcement
Pricing
Other
Place of performance
Baltimore, MD 21201, USA

Award details come from SAM.gov/FPDS.

About this award

The Defense Advanced Research Projects Agency (DARPA) awarded an $1.8M Other Transaction Agreement to Kalocyte Inc. on August 14, 2025, for the production of Good Laboratory Practice (GLP)-compliant ErythroMer for Investigational New Drug (IND) enabling animal studies. The contract, which is not subject to a set-aside designation, extends through August 14, 2026, and will be performed in Baltimore, Maryland. Kalocyte Inc., a small disadvantaged biotech firm, is developing ErythroMer, a bio-inspired artificial red blood cell substitute designed to address life-threatening blood loss in military and civilian trauma scenarios.

This effort builds on Kalocyte's prior federal investments from the Defense Health Agency and the National Institutes of Health to advance the ErythroMer technology platform. The company has established partnerships with the University of Illinois at Urbana-Champaign for manufacturing and Washington University in St. Louis for in vivo efficacy validation. Under this contract, Kalocyte will produce GLP-grade ErythroMer necessary to support regulatory submissions, including animal studies required for IND applications. The deliverables represent a critical transition from research and development to pharmaceutical manufacturing standards, positioning the technology for potential clinical advancement as a next-generation resuscitation fluid for hemorrhagic shock management across multiple trauma scenarios.

Quick answers

Who was awarded contract HR00112590241?

HR00112590241 was awarded to Kalocyte Inc. by Defense Advanced Research Projects Agency (Department of Defense) on August 14, 2025.

How much is contract HR00112590241 worth?

The government has obligated $1,799,993 on HR00112590241.

Was contract HR00112590241 competed?

The extent of competition for HR00112590241 was competed.

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