Columbia - tearwise | oculab
Active Other Transaction Agreement Awarded Last action
- Contract number
- 140D042690006
- Awardee
-
The Trustees Of Columbia University In The City Of New York UEI F4N1QNPB95M4
- Awarding agency
-
Interior Business Center
Office of Policy Management and Budget, Department of the Interior
- Obligated
- $9,364,971
Award facts
- Contract value 54% obligated
-
- $9,364,971.00 Current, with exercised options
- $17,341,223.00 Potential, with all options
- Completion date 20% complete
-
- Current, with exercised options
- Potential, with all options
- Funding agency
- National Institutes of Health Department of Health and Human Services
- NAICS code
- Not on record
- Competition
- Competed Program Solicitation
- Pricing
- Other
- Place of performance
- New York, NY 10027, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Original award | $9,364,971 |
About this award
The National Institutes of Health awarded an Other Transaction Agreement to The Trustees of Columbia University in the City of New York, doing business as Columbia University, for the COLUMBIA-TEARWISE | OCULAB medical device and therapeutic development effort, with a ceiling value of $17.3 million on January 30, 2026. This OTA sits outside the FAR. The effort addresses dry eye disease (DED), a multifactorial condition involving tear film instability, inflammation, and ocular surface damage, with a focus on markers and therapeutics for DED associated with Sjogren's syndrome and neurotrophic keratopathy. Subaward descriptions identify the work as an ARPA-H project called TEARWISE (Tear-film Electronic Active Release and Wireless Immune-shielded Sensing Encapsulation). The agreement runs through January 29, 2030, with performance in New York, New York 10027.
Two subawards, both dated June 17, 2026, carry the named team. Quicksilver Biosciences Inc. is developing the fabrication process for integrating single-molecule field-effect transistor (smFET) devices onto the TEARWISE application-specific integrated circuit (ASIC). The University of Maryland, College Park is developing mathematical models for DED and designing algorithms for energy-efficient optogenetic toggle switch controllers using machine and control theory.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Quicksilver Biosciences Inc. | $65,000 | |
| University Of Maryland, College Park | $25,000 |
Quick answers
Who was awarded contract 140D042690006?
140D042690006 was awarded to The Trustees Of Columbia University In The City Of New York by Interior Business Center (Office of Policy Management and Budget) on January 30, 2026.
How much is contract 140D042690006 worth?
The government has obligated $9,364,971 on 140D042690006. Its potential value, with all options, is $17,341,223.
Which agency awarded contract 140D042690006?
Interior Business Center (Office of Policy Management and Budget) awarded 140D042690006, with funding from National Institutes of Health (Department of Health and Human Services).
Was contract 140D042690006 competed?
The extent of competition for 140D042690006 was competed.
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