Advanced analysis for precision cancer therapy (adapt) TA1 P5220: dynamic digital tumors for precision oncology
Active Other Transaction Agreement Awarded Last action
- Contract number
- 140D042590013
- Awardee
-
University Of California, San Diego UEI UYTTZT6G9DT1
- Awarding agency
-
Interior Business Center
Office of Policy Management and Budget, Department of the Interior
- Obligated
- $11,577,175
Award facts
- Contract value 49% obligated
-
- $11,577,175.00 Current, with exercised options
- $23,558,029.00 Potential, with all options
- Completion date 24% complete
-
- Current, with exercised options
- Potential, with all options
- Funding agency
- National Institutes of Health Department of Health and Human Services
- NAICS code
- Not on record
- Competition
- Competed Program Solicitation
- Pricing
- Other
- Place of performance
- La Jolla, CA 92093, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Original award | $11,577,175 |
About this award
The National Institutes of Health awarded an Other Transaction Agreement to University of California, San Diego with a ceiling value of $23,558,029 on May 20, 2025, for the Advanced Analysis for Precision Cancer Therapy (ADAPT) TA1 P5220 effort to develop dynamic digital tumors for precision oncology. The agreement sits outside the FAR and operates under OTA statutory authority. Performance extends through May 19, 2031, with work conducted in La Jolla, California.
The project builds next-generation predictive oncology models to enable real-time, accurate drug recommendations for cancer treatment, focusing on breast, lung, and colon cancers. UC San Diego leads the overall effort and oversees task area 1.3, which encompasses development, optimization, deployment, and evaluation of computational drug sensitivity prediction approaches informed by patient molecular data.
Major subcontractors include the Regents of the University of Minnesota, which develops computational drug sensitivity prediction models under the direction of R. Stephanie Huang; Beckman Research Institute of the City of Hope, awarded $750,000 for tumor evolution mechanisms and predictive modeling work leveraging experimental, computational, and mathematical methods under Dr. Aritro Nath; University of Washington, awarded $499,744 for advances in explainable AI to identify early driver events in cancer pathogenesis and tumor microenvironment dysfunction; and University Health Network in Toronto, awarded $248,378 to construct and validate predictive models using multimodal data to forecast patient response to anticancer therapies through radiomics and histomics modeling under Benjamin Haibe-Kains.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Regents Of The University Of Minnesota | $500,000 | |
| Beckman Research Institute Of The City Of Hope | $1,500,001 | |
| University Health Network | $248,378 | |
| University Of Washington | $499,744 |
Quick answers
Who was awarded contract 140D042590013?
140D042590013 was awarded to University Of California, San Diego by Interior Business Center (Office of Policy Management and Budget) on May 20, 2025.
How much is contract 140D042590013 worth?
The government has obligated $11,577,175 on 140D042590013. Its potential value, with all options, is $23,558,029.
Which agency awarded contract 140D042590013?
Interior Business Center (Office of Policy Management and Budget) awarded 140D042590013, with funding from National Institutes of Health (Department of Health and Human Services).
Was contract 140D042590013 competed?
The extent of competition for 140D042590013 was competed.
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