BIO-insync: BIO-integrated implantable systems for cell-based sensing and therapy

Active Other Transaction Agreement Awarded Last action

Contract number
140D042490005
Awardee
Awarding agency
Obligated
$29,730,686

Award facts

Contract value 71% obligated
  • $29,730,686.00 Current, with exercised options
  • $41,977,673.00 Potential, with all options
Completion date 35% complete
  • Current, with exercised options
  • Potential, with all options
Funding agency
National Institutes of Health Department of Health and Human Services
NAICS code
Not on record
Competition
Competed Program Solicitation
Pricing
Other
Place of performance
Pittsburgh, PA 15213, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00006 $0
Other Administrative Action P00005 $0
Supplemental Agreement for work within scope P00004 $0
Other Administrative Action P00003 $0
Other Administrative Action P00002 $0
Other Administrative Action P00001 · BIO-insync $0
Original award $29,730,686

About this award

The National Institutes of Health awarded an Other Transaction Agreement to Carnegie-Mellon University for BIO-INSYNC (Bio-Integrated Implantable Systems for Cell-Based Sensing and Therapy) on September 17, 2024, with a ceiling value of $41,977,673 and an ultimate completion date of September 16, 2030. This OTA sits outside the FAR and operates under alternative acquisition authority.

Work is performed in Pittsburgh, Pennsylvania. Carnegie-Mellon University leads the effort with subcontractors including the University of Pittsburgh (subawards issued October 29, 2025, and December 1, 2025), the University of Florida's Office of Engineering Research (subaward issued October 20, 2025), and Ginkgo Bioworks, Inc. (subaward issued September 17, 2024, for cell engineering, optimization, and production scaling to support standardized procedures for discovering, selecting, screening, engineering, and optimizing GMP-grade induced pluripotent stem cells for suitability in microenvironments within implantable device prototypes designed to correct metabolic dysfunction in patients with thyroid disorders).

Subawards

Subcontractor Amount Awarded
University Of Pittsburgh - Of The Commonwealth System Of Higher Education BIO-INSYNC: BIO-INTEGRATED IMPLANTABLE SYSTEMS FOR CELL-BASED SENSING AND THERAPY BIO-INSYNC: Biointegrated Implantable Systems for Cell-based Sensing and… $286,877
University Of Pittsburgh - Of The Commonwealth System Of Higher Education BIO-INSYNC: BIO-INTEGRATED IMPLANTABLE SYSTEMS FOR CELL-BASED SENSING AND THERAPY BIO-INSYNC: Bio- integrated Implantable Systems for Cell-based Sensing and… $193,242
University Of Florida BIO-INSYNC: BIO-INTEGRATED IMPLANTABLE SYSTEMS FOR CELL-BASED SENSING AND THERAPY BIO-INSYNC: Biointegrated Implantable Systems for Cell-based Sensing and… $357,824
Ginkgo Bioworks, Inc. BIO-INSYNC Support cell engineering, optimization, and production scaling support. Establish standardized procedures for discovering, selecting, screening,… $3,819,525

Quick answers

Who was awarded contract 140D042490005?

140D042490005 was awarded to Carnegie-Mellon University by Interior Business Center (Office of Policy Management and Budget) on September 17, 2024.

How much is contract 140D042490005 worth?

The government has obligated $29,730,686 on 140D042490005. Its potential value, with all options, is $41,977,673.

Which agency awarded contract 140D042490005?

Interior Business Center (Office of Policy Management and Budget) awarded 140D042490005, with funding from National Institutes of Health (Department of Health and Human Services).

Was contract 140D042490005 competed?

The extent of competition for 140D042490005 was competed.

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