Gene therapy using plants

Active Other Transaction Agreement Awarded Last action

Contract number
140D042490002
Awardee
Awarding agency
Obligated
$46,567,436

Award facts

Contract value 76% obligated
  • $46,567,436.00 Current, with exercised options
  • $61,152,930.00 Potential, with all options
Completion date 52% complete
  • Current, with exercised options
  • Potential, with all options
Funding agency
National Institutes of Health Department of Health and Human Services
NAICS code
Not on record
Competition
Competed Program Solicitation
Pricing
Other
Place of performance
San Diego, CA 92126, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00006 $0
Other Administrative Action P00005 $0
Other Administrative Action P00004 $0
Supplemental Agreement for work within scope P00003 $0
Exercise an Option P00002 $16,304,480
Other Administrative Action P00001 · Transformative manufacturing of AAV and other gene therapies using rapid, safe, highly scalable, and cost-effective production in whole plants. $0
Original award $30,262,956

About this award

The National Institutes of Health awarded an Other Transaction Agreement to Vecprobio Inc. (operating as Cirsium Biosciences) for transformative manufacturing of adeno-associated virus (AAV) and other gene therapies using plant-based production systems, with a ceiling value of $61.15 million and an award date of September 17, 2024.

The agreement supports rapid, safe, highly scalable, and cost-effective production of gene therapies in whole plants. Performance concludes by September 16, 2028. Work is performed in San Diego, California. As an Other Transaction Agreement, this effort sits outside the Federal Acquisition Regulation and leverages alternative authorities for prototype development and innovative manufacturing approaches in the gene therapy space.

Quick answers

Who was awarded contract 140D042490002?

140D042490002 was awarded to Vecprobio Inc. by Interior Business Center (Office of Policy Management and Budget) on September 17, 2024.

How much is contract 140D042490002 worth?

The government has obligated $46,567,436 on 140D042490002. Its potential value, with all options, is $61,152,930.

Which agency awarded contract 140D042490002?

Interior Business Center (Office of Policy Management and Budget) awarded 140D042490002, with funding from National Institutes of Health (Department of Health and Human Services).

Was contract 140D042490002 competed?

The extent of competition for 140D042490002 was competed.

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