Our studies will use the fruit fly, drosophila and the worm, c. Elegans to identify conserved mechanisms underlying the oxidative stress response to altered gravity. Space flight induces alterations…
Ended Grant For Research Awarded Last action
- Contract number
- 80NSSC22K0278
- Awardee
-
Sanford Burnham Prebys Medical Discovery Institute UEI PHMKYKKJLQS1
- Awarding agency
-
Shared Services Center
National Aeronautics and Space Administration
- Obligated
- $1,329,280
Award facts
- Contract value 100% obligated
- $1,329,280.00 Current and potential, with all options
- Completion date 100% complete
- Current and potential, with all options
- Contracting staff
- NAICS code
- Not on record
- Set-aside
- No set-aside
- Competition
- Full and Open Competition Basic Research
- Pricing
- Other
- Place of performance
- La Jolla, CA 92037, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Funding Only Action | -$20,000 | |
| Other Administrative Action | $0 | |
| Funding Only Action | $393,567 | |
| Funding Only Action | $373,567 | |
| Funding Only Action | $183,838 | |
| Funding Only Action | $86,805 | |
| Funding Only Action | $276,503 | |
| Other Administrative Action | $0 | |
| Original award | $35,000 |
Show all 11
About this award
Sanford Burnham Prebys Medical Discovery Institute (SBP), a nonprofit biomedical research organization based in La Jolla, California, received a $1.33 million research grant from a civilian federal agency effective January 1, 2022, with a completion date of March 31, 2026. The contract funds basic research investigating the physiological mechanisms underlying oxidative stress responses in altered gravity environments, utilizing model organisms including fruit flies (Drosophila) and nematodes (C. elegans). The research aims to identify conserved biological mechanisms that explain how space flight induces muscular and neurological changes, with particular focus on somatic and cardiac muscle alterations in the brain. This research has direct relevance to understanding how spaceflight-induced changes parallel those caused by prolonged bed rest on Earth and age-related decline.
The contract carries no set-aside designation and represents SBP's continued collaboration with federal agencies on sophisticated biomedical research projects. Given the study's focus on spaceflight physiology and altered gravity environments, this award likely supports NASA's human spaceflight research priorities aimed at understanding and mitigating the physiological effects of microgravity exposure on astronauts. SBP's extensive track record of federal research funding from agencies including the National Institutes of Health institutes and collaborative relationships with premier research institutions positions the organization to effectively execute this fundamental research project with potential applications extending to both space exploration and terrestrial medical understanding of aging and disease mechanisms.
Description
Our studies will use the fruit fly, drosophila and the worm, c. Elegans to identify conserved mechanisms underlying the oxidative stress response to altered gravity. Space flight induces alterations in somatic/cardiac muscle, as well as in the brain.
Quick answers
Who was awarded contract 80NSSC22K0278?
80NSSC22K0278 was awarded to Sanford Burnham Prebys Medical Discovery Institute by Shared Services Center (National Aeronautics and Space Administration) on January 1, 2022.
How much is contract 80NSSC22K0278 worth?
The government has obligated $1,329,280 on 80NSSC22K0278.
Was contract 80NSSC22K0278 competed?
The extent of competition for 80NSSC22K0278 was full and open competition.
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