This federal contract award from the National Aeronautics and Space Administration (NASA) was granted to the J. Craig Venter Institute, Inc. (JCVI), a non-profit genomic research organization, for a study on the impact of diet on the human immune system, gut microbiota, and nutritional status during spaceflight. The $232,937 grant will fund an interdisciplinary study to compare the effects of the current spaceflight diet to an "enhanced" diet with more omega-3 fatty acids, lycopene,...
This is a $29,439.93 grant awarded by NASA to Amentum Services, Inc. to study the microbiomes of leafy green vegetable crops grown during spaceflight on the International Space Station. The research aims to expand knowledge of how microbial organisms and communities associated with the Veggie plant growth system acclimate to and change over time in the spaceflight environment. This includes analyzing interactions between the plant microbiomes and the broader spacecraft environment, including...
This grant award to the J. Craig Venter Institute, Inc. is for a research project focused on understanding the mechanisms of antibiotic resistance and virulence in certain bacteria that have been identified in the water system of the International Space Station. The $137,075.84 award from the National Aeronautics and Space Administration will support genomic sequencing and transposon sequencing studies to assess the potential for increased virulence and antibiotic resistance in Burkholderia...
This is a $463,070 grant awarded by the National Aeronautics and Space Administration (NASA) to Northwestern University to conduct research on the impact of the spaceflight environment on the gastrointestinal microbiota and its connection to immune, metabolic, and psychological health. The award is not a set-aside contract. Northwestern University is the prime contractor, and the award has an ultimate completion date of August 31, 2025. This grant contributes to NASA's research efforts to...
This is a $143,397.62 grant for research awarded by the National Aeronautics and Space Administration (NASA) Shared Services Center to the Texas A&M University System Health Science Center. The grant, titled "ROSBIO New Investigator Award", aims to determine the impact of the shift in gut microbiome on the function of the lymphatic and immune systems of the gastrointestinal tract, as well as whether restoring a key metabolite, histidine, can alleviate the observed changes. The...
This is a $656,022 grant awarded by the National Aeronautics and Space Administration (NASA) to the Institute for Medical Research Inc. (IMR), a non-profit research organization. The grant will fund a project to identify strains of the single-cell green alga Chlamydomonas reinhardtii that exhibit optimal survival under the combined impacts of space radiation and microgravity beyond the Van Allen Belts. The goal is to identify Chlamydomonas strains with gene insertions that confer survival...
The National Aeronautics and Space Administration (NASA) awarded a $299,996.00 grant to The Regents of the University of California, San Francisco (UCSF) to conduct research aimed at using transcriptomic analyses to determine the gravity-sensitive molecular pathways important for organogenesis. This research aligns with NASA's Space Biology Plan to investigate the effect of the space environment on life and addresses how microgravity impacts tissue morphogenesis and stem cell differentiation....
This is a $139,986.55 grant awarded by the National Aeronautics and Space Administration (NASA) to the University of Florida (UF) Division of Sponsored Research to conduct research on the influence of microorganisms on the growth and protection of salad crops under conditions similar to the International Space Station (ISS). The objective is to develop a refined understanding of the plant microbiome of salad crops grown in plant growth chambers under previously used ISS growth conditions, and...
This is a $2,508,591.16 grant awarded by the National Aeronautics and Space Administration (NASA) to Arizona State University (ASU) to study the long-term, multigenerational effects of microgravity on microbial populations. The research aims to characterize genomic, epigenetic, and transcriptomic changes in the model pathogen Salmonella Typhimurium in response to chronic stress and selective pressures in the spaceflight environment. This grant addresses two key research emphases from NASA's...
This is a $828,256.73 grant award from the National Aeronautics and Space Administration (NASA) to Clemson University's Division of Research to develop synthetic biology technologies that can convert human waste and other in-situ resources into food, nutraceuticals, medicine, and materials for long-term space travel missions. The project focuses on engineering yeast to convert carbon dioxide, algae biomass, and human urine into nutritional omega-3 fats and 3D printable plastics. This work...
This is a $400,616 grant awarded by the National Aeronautics and Space Administration (NASA) to the J. Craig Venter Institute, Inc. (JCVI), a non-profit genomic research organization. The grant aims to study the effects of an "enhanced" spaceflight diet, with increased consumption of foods rich in omega-3 fatty acids, lycopene, flavonoids, fruits, and vegetables, on immune function, gut microbiota, and nutritional status of crew members in ground-based analogs and on International Space Station (ISS) missions. The study will compare the enhanced diet to the current spaceflight diet, with the goal of improving crew health and adaptation to spaceflight. The grant falls under NASA's research emphasis on understanding how complex organisms adapt to spaceflight. There is no set-aside designation for this award, and the ultimate completion date is March 31, 2025.