New lites order task order 0010 cavalier trial

Ended Awarded Last action

Contract number
W81XWH22F0118
Awardee
Awarding agency
Obligated
$11,999,380

Award facts

Opportunity
  • W81XWH16R0033 Solicitation number
Contract value 100% obligated
$11,999,380.00 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
Contracting staff
Set-aside
No set-aside
Competition
Full and Open Competition Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Pittsburgh, PA 15260, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00003 · Calcium and vasopressin following injury early resuscitation clinical trial $0
Other Administrative Action P00002 · Cavalier trial $0
Supplemental Agreement for work within scope P00001 · Correct contractor name. Add incremental funds. Per section 711 of the 2019 ndaa, usamraa transferred to DHA 10/01/2022. $4,028,570
Original award $7,970,810

About this award

The Defense Health Agency issued a delivery order to the University of Pittsburgh on September 22, 2022, with a ceiling value of $11,999,380 for the LITES Study Task Order 0010 CAVALIER (Calcium and Vasopressin Following Injury Early Resuscitation) clinical trial, a multi-year Phase II double-blinded, multi-center, prehospital and early in-hospital randomized trial. The order carries cost-no-fee pricing and is set to complete on September 22, 2026.

Place of performance is Pittsburgh, PA. The trial is designed to determine whether prehospital calcium supplementation, early in-hospital vasopressin infusion, or both as compared to placebo result in lower 30-day mortality in patients at risk of hemorrhagic shock. Secondary objectives assess 6-hour, 24-hour, and in-hospital mortality; death from hemorrhage and brain injury; transfusion requirements; Multiple Organ Failure incidence; nosocomial infection rates; time to hemostasis; coagulopathy by thromboelastography; and ICU-free and hospital-free days.

Subcontractors functioning as clinical trial sites include the University of Washington, University of Miami, University of Colorado-Denver, The Ohio State University, University of New Mexico Health Sciences Center, Denver Health and Hospital Authority, Hennepin Healthcare Research Institute, University of Maryland Baltimore, University of Missouri, University of Arkansas for Medical Sciences, University of Mississippi Medical Center, Allegheny Singer Research Institute, Dignity Community Care, Mount Carmel Health System, University of Arizona, and Texas Tech University Health Sciences Center. The multi-site enrollment spans 11 Level I trauma centers across the United States.

Subawards

Subcontractor Amount Awarded
University Of Washington NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL Serve as a clinical site for Task Order 010 $560,000
University Of Miami NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL Determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo are… $540,000
Dignity Community Care NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL To serve as a clinical site for LITES Study Task Order 010: CAlcium and VAsopressin following Injury Early… $200,000
The Regents Of The University Of Colorado NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL To serve as a clinical site for LITES Study Task Order 010: CAlcium and VAsopressin following Injury Early… $195,000
Mount Carmel Health System NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL Determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo results in… $195,000
The Ohio State University NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $580,000
University Of New Mexico NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL Cavalier Trial $677,000
Denver Health And Hospital Authority NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $730,000
Hennepin Healthcare Research Institute NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $620,200
University Of Maryland, Baltimore NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $500,000
University Of Missouri System NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $567,000
University Of Arkansas For Medical Sciences NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL New LITES Order Task Order 0010 Cavalier Trial $275,000
Allegheny Singer Research Institute NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL Determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo results in… $531,700
University Of Washington CAVALIER TRIAL Serve as a clinical site for Task Order 010: CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) trial, a 4-year (3-year… $500,000
University Of Mississippi Medical Center CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the safety and efficacy of… $500,000
University Of Miami CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the safety and efficacy of… $500,000
Denver Health And Hospital Authority CAVALIER TRIAL Double-blind, multi-center, prehospital and early in-hospital phase randomized trial utilizing 11 Level I trauma centers designed to determine… $500,000
University Of Arizona NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the… $500,000
Texas TECH University Health Sciences Center NEW LITES ORDER TASK ORDER 0010 CAVALIER TRIAL To determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo results… $559,000
University Of Arizona CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the safety and efficacy of… $500,000
Texas TECH University Health Sciences Center CAVALIER TRIAL To determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo results in lower 30-day mortality in… $500,000
The Administrators Of Tulane Educational Fund CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the safety and efficacy of… $500,000
Hennepin Healthcare Research Institute CAVALIER TRIAL The aims of the CAlcium and VAsopressin post-Injury Early Resuscitation (CAVALIER) trial are to determine the safety and efficacy of… $500,000
University Of New Mexico CAVALIER TRIAL Determine whether prehospital calcium, early in-hospital vasopressin, or both as compared to placebo results in lower 30-day mortality in… $500,000
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Quick answers

Who was awarded contract W81XWH22F0118?

W81XWH22F0118 was awarded to University Of Pittsburgh - Of The Commonwealth System Of Higher Education by Defense Health Agency (Department of Defense) on September 22, 2022.

How much is contract W81XWH22F0118 worth?

The government has obligated $11,999,380 on W81XWH22F0118.

Is contract W81XWH22F0118 an order under another contract?

Yes. W81XWH22F0118 is a delivery order under W81XWH16D0024, an indefinite delivery contract.

Was contract W81XWH22F0118 competed?

The extent of competition for W81XWH22F0118 was full and open competition.

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