Delivery Order HHSN261201200026I-HHSN26100002

The U.S. Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $204,715.60 firm-fixed-price purchase order to Charles River Laboratories, Inc. to conduct a non-GLP 50 antisense oligonucleotide (ASO) liver toxicity study in mice. The purpose is to develop a predictive model of candidate ASO therapies' safety and acute toxicity, supporting NCATS' efforts to accelerate the development of effective treatments for...

This cost-plus-fixed-fee delivery order from the Department of Health and Human Services' National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) to Battelle Memorial Institute is for $7.59 million to support preparedness for testing NIAID priority vaccines in general safety and toxicology studies. The work includes Chinese cynomolgus non-human primate testing and transportation from Envigo Global Services, procurement of ferrets from Triple F Farms, and...

This is a $4,565 firm fixed price purchase order awarded to Envigo Bioproducts Inc. by the National Institute of Allergy and Infectious Diseases, a component of the U.S. Department of Health and Human Services. The contract is for the provision of 30 nude mice for antibody production. No set-aside designation was used. Envigo Bioproducts Inc. is a discovery and development contract research organization that has previously provided specialized biomedical products and services, including mice, to...

This is a task order awarded by the Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases to Battelle Memorial Institute, doing business as Battelle, a nonprofit research and development organization, to design, conduct, and assess the immunogenicity and efficacy of a plague vaccine candidate formulated with IL-2 alum-cytuvax or other novel adjuvant in mice. The task order is part of the Evaluation and Testing...

This contract award to Gempharmatech LLC, a foreign-owned biotechnology company in San Diego, California, is for a $58,936 fixed-price purchase order to evaluate the safety of the compound YC1 in mice with humanized SULT1A1 proteins versus standard mouse SULT1A1 proteins. The contract was awarded by the National Center for Advancing Translational Sciences (NCATS), which operates under the National Institutes of Health within the Department of Health and Human Services. The objective is to...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded Arisan Therapeutics Inc. a $3.69M definitive contract on September 22, 2023, to conduct non-clinical Good Laboratory Practice (GLP) in vivo genotoxicity and reproductive toxicology studies, as well as GLP development and reproductive/developmental/adult toxicology (DART) studies. The contract, which carries a cost-plus-fixed-fee pricing structure with no set-aside designation, is scheduled for completion by December 31,...

This firm fixed-price delivery order contract was awarded by the Food and Drug Administration (FDA) to Integrated Laboratory Systems, LLC (ILS), a for-profit research and testing services company. The contract, valued at $88,156.00, is for a pilot study on the in vivo genetic toxicity of the chemical NNK (nicotine-derived nitrosamine ketone) in mice using the intraperitoneal route of administration. This contract is part of a larger $7.8 million indefinite delivery contract (IDC) awarded by...

The Centers for Disease Control and Prevention awarded Abcellera Biologics Inc. a definitive fixed price contract valued at $884,000 to provide a transgenic mouse model capable of generating humanized antibodies against influenza viruses. The original solicitation sought proposals for a mouse engineered with human immunoglobulin gene segments to better recapitulate the human antibody repertoire when testing candidate virus strains and developing antibodies. Under the contract, Abcellera will...

This is a federal contract award from the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), to Charles River Laboratories, Inc. The $557,514.90 firm-fixed-price contract is for the manufacture and safety testing of experimental virus vaccines. The contract is not set aside for any specific business type. Charles River Laboratories is a global contract research organization that provides essential products and services to...

This is a $4,626,893.20 delivery order contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the Department of Health and Human Services (HHS), to Battelle Memorial Institute. The contract is for the evaluation of filovirus vaccines in general use prophylaxis (GUP) immunogenicity and filovirus challenge studies. Key subcontractors include Integrated Biotherapeutics, LLC, a small disadvantaged business, which provided services related to filovirus...