Delivery Order HHSF223201310034I-HHSF22301002T

The Food and Drug Administration (FDA) awarded a $3.4M firm fixed-price contract to The Fox Foundation Inc. on September 24, 2024, to conduct a clinical laboratory study investigating the abuse liability of electronic nicotine delivery systems (ENDS) formulated with non-tobacco nicotine (NTN) compared to tobacco-derived nicotine (TDN). The three-year contract, which extends through September 2027, requires The Fox Foundation to execute a randomized, double-blinded, within-subjects crossover...

Technical Resources International, Inc. (TRI) has been awarded a firm fixed price purchase order valued at one million six hundred twenty four thousand one hundred twenty two dollars and twenty cents ($1,624,122.20) by the Department of Health and Human Services' Food and Drug Administration (FDA) to assess nicotine dose discrimination in marketed cigarettes. This purchase order was issued under an indefinite delivery/indefinite quantity contract held by TRI with the National Institutes of...

The Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences awarded a $134,500 firm fixed price purchase order to Xenobiotic Laboratories Inc. Biotesting Division for assessment of inhibition activity and substrate potential of two test articles for major human drug transporters. The solicitation requested the prime contractor evaluate Mitragynine and its metabolite 7-hydroxymitragynine to support drug development, using study...

This is a delivery order awarded by the Department of Health and Human Services, National Institutes of Health, National Center for Advancing Translational Sciences (NCATS) to IIT Research Institute, a non-profit research arm of Illinois Institute of Technology. The $1,759,590.00 cost-plus-fixed-fee contract provides non-clinical safety assessment of drinabant, a cannabinoid receptor (CB-1) antagonist, for acute cannabinoid overdose. The work will be performed in Chicago, Illinois and is part of...

The National Institute on Drug Abuse (NIDA) awarded a firm fixed-price purchase order to Nikolay Novikov valued at $76,116.30 for a fee-for-service study examining the pharmacology and physiology of the substantia nigra and basal ganglia. The contract period ran from November 1, 2009 through September 30, 2010, with an ultimate completion date of September 29, 2010. The work was performed in Bethesda, Maryland, and no set-aside designation was applied to this award. This study supports NIDA's...

The U.S. National Institute on Drug Abuse (NIDA) awarded a $1,899,037.00 cost-plus-fixed-fee delivery order contract to Advanced Bioscience Laboratories, Inc. (ABL) for the manufacture and preclinical testing of site blocking oligonucleotides (SBO) for neurological-related disorders. This award is part of a larger $149.2 million indefinite delivery vehicle (IDV) contract with NIDA for Manufacturing and Nonclinical Studies Support for the Development of Therapeutic Biotechnology Products for...

Xenobiotic Laboratories Inc. Biotesting Division was awarded a $71,740 firm fixed price purchase order by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to assess the cytochrome P450 (CYP450) enzyme induction potential of two test articles. Performance will take place in Plainsboro Township, New Jersey from August 2023 through March 2024. The award is in response to a solicitation requesting evaluation of the test...

The Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse awarded a $43,061.60 firm fixed price purchase order to Med Associates, Inc. for self-administration chambers to support research into brain mechanisms of compulsive drug use. Per the original solicitation, the Neuroimaging Research Branch requires additional self-administration training apparatuses for laboratory rats to self-administer compounds like methamphetamine while applying...

This is a delivery order contract awarded by the Food and Drug Administration (FDA) to Lovelace Biomedical and Environmental Research Institute, Inc. (LBERI), a non-profit research organization, to develop a standard guideline protocol for rodent tobacco smoke inhalation studies. The contract has a ceiling value of $1,373,599.00 and is a firm fixed-price task order issued under the "In Vivo Toxicology of Tobacco 2015-2020" indefinite-delivery, indefinite-quantity (IDIQ) contract. The...

The U.S. National Institute on Drug Abuse (NIDA), a civilian agency, awarded a $78,857.55 firm fixed-price purchase order contract to Med Associates, Inc., a for-profit, woman-owned manufacturer, to provide a Rat Self-Administration Chambers System. This sole-source contract was issued without a set-aside designation to procure 13 self-administration chambers and 1 laptop for the NIDA Neuroimaging Research Branch's ongoing animal studies examining the behavioral effects of abused drugs like...