Manufacture of plasmid DNA drug substance and drug product

Active Awarded Last action

Contract number
75N91024F00002
Awardee
Awarding agency
Obligated
$2,790,973

Award facts

Opportunity
  • MARTP1202402 Solicitation number
Contract value 100% obligated
$2,790,973.00 Current and potential, with all options
Completion date 58% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Rockville, MD 20850, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Change Order P00002 $1,266,044
Other Administrative Action P00001 $0
Original award $1,524,929

About this award

The National Cancer Institute awarded a delivery order valued at $2.79 million to Mriglobal (doing business as Midwest Research Institute) on September 25, 2024, for the manufacture of plasmid DNA drug substance and drug product. This contract, which is not subject to any small business set-aside designation, is structured as a cost-plus-no-fee arrangement with a completion date of April 30, 2028, and will be performed in Rockville, Maryland. Plasmid DNA represents an important class of therapeutic agents in cancer treatment and genetic medicine, and this manufacturing contract supports NCI's broader mission to advance cancer research and develop innovative treatment modalities.

Mriglobal is a Kansas City-based nonprofit research organization with extensive federal contracting experience across multiple agencies and a specialized focus on pharmaceutical manufacturing and drug development. The organization holds numerous significant indefinite delivery contracts, including substantial arrangements with the National Cancer Institute for research and repository services, and has demonstrated expertise in manufacturing clinical-grade pharmaceuticals and providing chemistry, manufacturing, and controls services across government and commercial sectors. This delivery order leverages Mriglobal's established capabilities in drug substance and product manufacturing to support NCI's therapeutic development initiatives.

Quick answers

Who was awarded contract 75N91024F00002?

75N91024F00002 was awarded to Mriglobal by National Cancer Institute (National Institutes of Health) on September 25, 2024.

How much is contract 75N91024F00002 worth?

The government has obligated $2,790,973 on 75N91024F00002.

Is contract 75N91024F00002 an order under another contract?

Yes. 75N91024F00002 is a delivery order under 75N91023D00010, an indefinite delivery contract.

Was contract 75N91024F00002 competed?

The extent of competition for 75N91024F00002 was full and open competition.

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