Computational design of enzymatic prophylactics and/or therapeutics for chemical warfare nerve agents

Ended Definitive Contract Awarded Last action

Contract number
HDTRA122C0038
Awardee
Awarding agency
Obligated
$1,507,784

Award facts

Contract value 100% obligated
$1,507,783.93 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources · 1 offer Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Fort Belvoir, VA 22060, USA
Research
SBIR Program Phase II Action
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00005 $0
Other Administrative Action P00004 $0
Additional Work (new agreement, FAR part 6 applies) P00003 $389,351
Supplemental Agreement for work within scope P00002 $0
Other Administrative Action P00001 $0
Original award $1,118,433

About this award

Arzeda Corp, a Seattle-based biotechnology company specializing in artificial intelligence-driven enzyme design, was awarded a $1.51 million Small Business Innovation Research Phase II contract by the Defense Threat Reduction Agency in August 2022. The definitive, firm-fixed-price contract, set aside for small businesses, focuses on the computational design of enzymatic prophylactics and therapeutics specifically targeting chemical warfare nerve agents. Work will be performed at Fort Belvoir, Virginia, with an ultimate completion date of October 9, 2025. This award reflects DTRA's investment in innovative biodefense solutions and demonstrates Arzeda's technical capabilities in developing sophisticated enzymatic countermeasures for national defense applications.

The SBIR Phase II award builds upon Arzeda's demonstrated expertise in advanced protein engineering and bioconversion technologies. The company's broader portfolio includes NSF-funded research on cell-free enzymatic systems for carbon dioxide conversion and biocatalytic processes for sustainable chemical production, positioning the firm as a capable developer of cutting-edge enzymatic solutions. The contract represents a significant research and development effort within the federal biodefense and life sciences sector, leveraging computational biology approaches to address critical national security challenges related to chemical warfare agent mitigation.

Quick answers

Who was awarded contract HDTRA122C0038?

HDTRA122C0038 was awarded to Arzeda Corp by Defense Threat Reduction Agency (Department of Defense) on August 29, 2022.

How much is contract HDTRA122C0038 worth?

The government has obligated $1,507,784 on HDTRA122C0038.

Was contract HDTRA122C0038 competed?

The extent of competition for HDTRA122C0038 was full and open competition after exclusion of sources. The government received 1 offer. It was set aside: Total Small Business.

On GovTribe

See this award's full record

  • Every transaction and funding action
  • The awardee's other awards and teaming partners
  • Similar awards and recompete opportunities
  • Ask GovTribe AI about this award